Toremifene

When ATH:
L02BA02

Characteristic.

The antitumor agent (antiestrogen).

Pharmacological action.
Antiestrogens, antitumor.

Application.

Breast cancer in women menopause.

Contraindications.

Hypersensitivity, pregnancy.

Pregnancy and breast-feeding.

Category actions result in FDA - D. (There is evidence of the risk of adverse effects of drugs on the human fetus, obtained in research or practice, However, the potential benefits, associated with drugs in pregnant, may justify its use, in spite of the possible risk, if the drug is needed in life-threatening situations or severe disease, when safer agents should not be used or are ineffective.)

Side effects.

Dizziness, nausea, feeling the heat, increased sweating, dyspepsia, hypercalcemia, thrombocytopenia.

Cooperation.

Preparations, reduce the excretion of calcium by the kidneys (thiazide diuretics), increase the risk of hypercalcemia.

Dosing and Administration.

Inside. The usual dose 60 mg daily, if necessary (in case of failure of other endocrine or cytotoxic therapy) - To 240 mg per day (2 × 120 mg).