Tianeptine

When ATH:
N06AX14

Characteristic.

Tricyclic antidepressants.

Pharmacological action.
Antidepressant.

Application.

Depressions.

Contraindications.

Hypersensitivity, childhood and adolescence (to 15 years), concomitant use of non-selective MAO inhibitors.

Restrictions apply.

Pregnancy, lactation.

Pregnancy and breast-feeding.

Should be avoided in pregnancy, tk. clinical data on the safety of pregnant women lacking. At the time of treatment should stop breastfeeding (tricyclic antidepressants penetrate into breast milk).

Side effects.

From the nervous system and sensory organs: dizziness, headache, insomnia, daytime sleepiness, poor concentration, nightmares, asthenia, lipotimiya, fainting, tremor.

Cardio-vascular system and blood (hematopoiesis, hemostasis): tachycardia, arrythmia, angina, chest pain.

From the respiratory system: discomfort in breathing, difficulty breathing, anchone, the feeling of "lump" in the throat.

From the digestive tract: dry mouth, anorexia, epigastric pain and abdominal, nausea, vomiting, constipation, flatulence.

Other: feeling the heat, flushing, pain syndrome (myalgia, pain in the lumbosacral spine).

Cooperation.

Incompatible with MAO inhibitors (may develop collapse, a sudden increase in blood pressure, hyperthermia, convulsions, until death).

Overdose.

Treatment: removal of the drug, gastric lavage; requires monitoring of heart function, light, kidney, metabolic processes; simptomaticheskaya therapy (if necessary - IVL, correction of renal function, metabolic disorders and others.).

Dosing and Administration.

Inside (before eating), adult on 12,5 mg 3 once a day (older people 70 years of age and patients with renal insufficiency is on 12,5 mg 2 once a day). In patients with chronic alcoholism (cirrhotic liver or without) dose adjustment is not required.

Precautions.

Continuous monitoring of patients, especially at the beginning of treatment due to the likelihood of suicide attempts in the background of the doldrums. When planning for general anesthesia must notify anesthesiologist about treatment tianeptinom and cancel receiving medication for 24-48 hours before surgery. When providing emergency surgical care requires strict monitoring of the patient during surgery.

Complete treatment of gradual (7-14 Days) reduction of the daily dose. When switching from reception of MAO inhibitors in the tianeptine need a break of at least 2 Sun, and when his replacement MAO inhibitors-break in 24 no. It should refrain from activities potentially hazardous activities, require increased attention and psychomotor speed reactions (due to a possible decrease in concentration).