TARIVID
Active material: Ofloxacin
When ATH: J01MA01
CCF: Fluoroquinolone antibacterial drug
When CSF: 06.17.02.01
Manufacturer: Aventis Pharma Germany GmbH (Germany)
DOSAGE FORM, COMPOSITION AND PACKAGING
Solution for infusion clear, greenish yellow.
| 1 ml | |
| ofloxacin hydrochloride | 2.2 mg, |
| that corresponds to the content of ofloxacin | 2 mg |
Excipients: sodium chloride, 1 N hydrochloric acid (to bring the pH level), water d / and.
100 ml – colorless glass vials (1) – packs cardboard.
| Pills, Film-coated | 1 tab. |
| ofloxacin | 200 mg |
10 PC. – packings Valium planimetric (1) – packs cardboard.
Pharmacological action
Pharmacological action – Antibacterial, bactericide.
Blocks of DNA gyrase, stop DNA replication in microbial cells.
Active against Pseudomonas, Haemophilus influenzae and E. coli, Shigella, Salmonella, meningococcus, gonokokkov, staphylococci, Legionella, mycoplasma, chlamydia etc..
Pharmacokinetics
Quickly and almost completely absorbed after oral administration, bioavailability - about 100%.
Cmax is reached after 30-60 minutes.
High concentrations are in the urine, saliva, mokrote, bile, skin, tissues, exudate and prostatic secretions. T1/2 — 5–7 ч. To 90% excreted by the kidneys in unchanged form.
Testimony
- respiratory tract infections,
- ENT,
- skin and soft tissue,
- abdomen (including pelvis),
- kidney and urinary tract,
- infections in obstetrics and gynecology,
- gonorrhea.
Dosage regimen
Inside, regardless of the meal, by 1 Table. (200 mg) 2 once a day, course - 7-10 days (not recommended for more than 8 Sun).
Gonorrhoea – 2 Table. single. The maximum daily dose – 0,8 g.
At impaired kidney function dose is calculated on the basis of the severity of kidney disease.
When severe infection – I / (infusion over 1 no) 0,2 d of 5% glucose solution.
Side effect
Dyspepsia, headache, dizziness, sleep disturbance, anxiety, reduction reaction, increased levels of bilirubin and liver enzymes, photosensitivity, allergic reactions (skin rash, swelling of the face, and vocal cords, suffocation, shock).
Contraindications
- hypersensitivity,
- epilepsy, age (to 18 years),
- CNS disorders with reduced seizure threshold
Pregnancy and lactation
Contraindicated.
Cautions
It should take into account a possible reduction in the rate of reaction (Be wary appoint the management of vehicles).
Overdose
These are not represented.
Drug Interactions
Efficiency is reduced (umenyshaetsya resorption) antaцidami.
Conditions and terms
Keep dry, at a temperature not higher 25 °C.
Do not freeze.
Shelf life – 5 years.
