Active material: Ofloxacin
When ATH: J01MA01
CCF: Fluoroquinolone antibacterial drug
When CSF: 06.17.02.01
Manufacturer: Aventis Pharma Germany GmbH (Germany)
Solution for infusion clear, greenish yellow.
| 1 ml | |
| ofloxacin hydrochloride | 2.2 mg, |
| that corresponds to the content of ofloxacin | 2 mg |
Excipients: sodium chloride, 1 N hydrochloric acid (to bring the pH level), water d / and.
100 мл – флаконы бесцветного стекла (1) – пачки картонные.
| Pills, Film-coated | 1 tab. |
| ofloxacin | 200 mg |
10 PC. – упаковки ячейковые контурные (1) – пачки картонные.
Фармакологическое действие – антибактериальное, bactericide.
Blocks of DNA gyrase, stop DNA replication in microbial cells.
Active against Pseudomonas, Haemophilus influenzae and E. coli, Shigella, Salmonella, meningococcus, gonokokkov, staphylococci, Legionella, mycoplasma, chlamydia etc..
Quickly and almost completely absorbed after oral administration, bioavailability - about 100%.
Cmax is reached after 30-60 minutes.
High concentrations are in the urine, saliva, mokrote, bile, skin, tissues, exudate and prostatic secretions. T1 / 2 - 5-7. To 90% excreted by the kidneys in unchanged form.
Inside, regardless of the meal, by 1 Table. (200 mg) 2 once a day, course - 7-10 days (not recommended for more than 8 Sun).
При гонорее – 2 Table. single. The maximum daily dose - 0,8 g.
At impaired kidney function dose is calculated on the basis of the severity of kidney disease.
При инфекциях тяжелого течения – в/в (infusion over 1 no) 0,2 d of 5% glucose solution.
Dyspepsia, headache, dizziness, sleep disturbance, anxiety, reduction reaction, increased levels of bilirubin and liver enzymes, photosensitivity, allergic reactions (skin rash, swelling of the face, and vocal cords, suffocation, shock).
Contraindicated.
It should take into account a possible reduction in the rate of reaction (Be wary appoint the management of vehicles).
These are not represented.
Efficiency is reduced (umenyshaetsya resorption) antaцidami.
Keep dry, at a temperature not higher 25 °C.
Do not freeze.
Shelf life - 5 years.
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