Sulfacetamide

When ATH:
S01AB04

Characteristic.

Сульфацетамид натрия — белый кристаллический порошок без запаха со слегка горьковатым вкусом. Easily soluble in water, practically insoluble in ethanol, ether, acetone, xloroforme.

Pharmacological action.
Antimicrobial, Antibacterial, bacteriostatic.

Application.

Eye drops and ointment for external use: conjunctivitis, .Aloe, purulent corneal ulcer, prevention and treatment of neonatal ophthalmia, gonococcal and chlamydial eye disease in adults. Solution for injection: pneumonia, purulent bronchitis, urinary tract infection.

Contraindications.

Hypersensitivity, toxic and allergic reactions to sulfonamides history.

Restrictions apply.

In / in the introduction contraindicated in severe diseases of the hematopoietic system and uremia.

Side effects.

Severe hypersensitivity reactions to sulfa drugs (Stevens-Johnson syndrome, fever, skin rash, disorders of the gastrointestinal tract, bone marrow depression).

Local reactions: burning, lacrimation, rez, itchy eyes, allergic reactions.

Cooperation.

Sulfacetamide incompatible with silver salts. The combined use of procaine and tetracaine reduces bacteriostatic effect.

Dosing and Administration.

Locally, parenterally. Locally: глазные капли закапывают по 1–2 капли в каждый конъюнктивальный мешок 4–6 раз в сутки. Для профилактики бленнореи у новорожденных — по 2 drops each conjunctival sac immediately after birth and 2 капли — через 2 no. Мазь закладывают за веко 3–4 раза в сутки.

In / in slowly (for not less than 5 m) по 3–5 мл 30% solution 2 раза в день с промежутком 12 no.

Precautions.

Use of an ophthalmic ointment may delay healing of the cornea.

Patients, having an increased sensitivity to furosemide, thiazide diuretics, sulfonylurea or carbonic anhydrase inhibitors, may be sensitive to sulfacetamide.