When ATH:
A11DA02
Pharmacological action
Means, регулирующее метаболические процессы в ЦНС – синтетическое соединение, similar in structure to thiamine (It has an open thiazole ring, more disulfide bond and lipophilic ester). It has a high efficacy in the symptomatic treatment of patients with functional asthenic conditions.
Pharmacokinetics
Абсорбция из ЖКТ – высокая, Cmax determined by 1-2 h after administration. T1/2 - About 5 no. Report the news. It is soluble in fats, easily penetrates through the BBB. Unlike thiamine, can accumulate in the cells of the reticular formation, hippocampus and dentate gyrus, and Purkinje cells and glomeruli of the granular layer of the cerebellar cortex.
Testimony
Asthenic conditions at Hypo- and beriberi, long illness, after surgery.
Dosage regimen
Inside, суточная доза – 400-600 mg, Duration of treatment is determined individually.
Side effect
Maybe: allergic reactions, excitation (elderly).
Contraindications
Childhood, pregnancy, lactation (breast-feeding), Hypersensitivity to sulbutiamine.
Pregnancy and lactation
Sulbutiamine is contraindicated during pregnancy and lactation (breast-feeding).
Cautions
It does not reduce the concentration of attention and speed of psychomotor reactions.
Drug Interactions
The data is not provided.
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