Sulbutyamyn

When ATH:
A11DA02

Pharmacological action

Means, regulating the metabolic processes in the CNS – synthetic compound, similar in structure to thiamine (It has an open thiazole ring, more disulfide bond and lipophilic ester). It has a high efficacy in the symptomatic treatment of patients with functional asthenic conditions.

Pharmacokinetics

Absorption from the gastrointestinal tract – high, C_max determined by 1-2 h after administration. T_1/2 – about 5 no. Report the news. It is soluble in fats, easily penetrates through the BBB. Unlike thiamine, can accumulate in the cells of the reticular formation, hippocampus and dentate gyrus, and Purkinje cells and glomeruli of the granular layer of the cerebellar cortex.

Testimony

Asthenic conditions at Hypo- and beriberi, long illness, after surgery.

Dosage regimen

Inside, daily dose – 400-600 mg, Duration of treatment is determined individually.

Side effect

Maybe: allergic reactions, excitation (elderly).

Contraindications

Childhood, pregnancy, lactation (breast-feeding), Hypersensitivity to sulbutiamine.

Pregnancy and lactation

Sulbutiamine is contraindicated during pregnancy and lactation (breast-feeding).

Cautions

It does not reduce the concentration of attention and speed of psychomotor reactions.

Drug Interactions

The data is not provided.