Struktum

Active material: Chondroitin sulfate
When ATH: M01AX25
CCF: Preparation, regulates the metabolism of the cartilage
ICD-10 codes (testimony): M15, M42
When CSF: 16.05.01
Manufacturer: PIERRE FABRE DRUG PRODUCTION (France)

Pharmaceutical form, composition and packaging

Capsules gelatin, blue, size №0; contents of capsules – Powder white-cream color, tolerance of conglomerates (komočkov), related to the peculiarities of the spatial structure.

Excipients: talc.

Ingredients of the capsule shell: gelatin, Titanium dioxide, indigo carmine.

12 PC. – blisters (5) – packs cardboard.

Pharmacological action

Struktum effect on metabolic processes in hyaline and fibrocartilage, reduces degenerative processes in the cartilage of joints, It stimulates the biosynthesis of glycosaminoglycans. It slows bone resorption and reduces calcium loss, accelerates bone regeneration. In applying the drug Struktum decreases pain and improves the mobility of the affected joints. The therapeutic effect persists for a long time after the end of therapy.

Pharmacokinetics

Absorption and distribution

After taking the drug inside more 70% Chondroitin sulfate is absorbed from the gastrointestinal tract. After receiving a single dose of a therapeutic medium C_max plasma levels achieved after 3-4 no, synovial fluid – through 4-5 no. The bioavailability of the drug is 13%. Chondroitin sulfate is accumulated in the synovial fluid.

Deduction

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Testimony

- Osteoarthritis (I-III stages);

- Intervertebral osteochondrosis.

Dosage regimen

Adults and adolescents 15 and older the drug is prescribed in a dose 1 g / day – by 500 mg 2 times / day. The recommended duration of treatment is the initial 6 Months. The therapeutic effect of the drug is maintained for a 3-5 months after cancellation depending on the location and severity. If necessary, you can repeat courses of treatment, the duration of which is determined individually.

Capsules taken orally, drinking water.

Side effect

From the digestive system: rarely – nausea, vomiting.

Allergic reactions: rarely – hives, эritema, itching.

Contraindications

- Children up to age 15 years (due to the lack of accurate data);

- Hypersensitivity to the drug.

Pregnancy and lactation

Struktum not recommended during pregnancy and lactation (breast-feeding) due to the lack of sufficient clinical data.

Cautions

With care prescribe a drug or bleeding tendency to bleeding.

Overdose

Symptoms: rarely – nausea, vomiting, diarrhea, Propafenone in extremely high doses (more 3 g / day) possible hemorrhagic rash.

Treatment: symptomatic therapy.

Drug Interactions

In an application with Struktum drug may increase the effect of indirect anticoagulants, antiplatelet agents and fibrinolytic.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 3 year.