STOPGRIPAN FORTE

Active material: Paracetamol, Phenylephrine, Pheniramine, Vitamin C
When ATH: N02BE51
CCF: The drug for the symptomatic treatment of acute respiratory diseases
When CSF: 03.02.01.03.01
Manufacturer: ratiopharm INDIA Pvt. Ltd. (India)

Pharmaceutical form, composition and packaging

◊ Powder for oral solution (blackcurrant) crystalline, from light pink to dark pink with blue crystals, with a characteristic smell of blackcurrant; prepared solution opaque, purple, with the smell of black currant.

Excipients: calcium phosphate, lemon acid, maltodextrin, sodium citrate dihydrate, sucrose, Titanium dioxide, etilmaltol, malic acid, blackcurrant flavor, dye brilliant blue, colorant sunset yellow, Ponceau 4R dye.

21.5 g – sachet (10) – packs cardboard.

Pharmacological properties

Combined preparation. Paracetamol okazыvaet zharoponizhayushtee and analygstychsskoe action. Fenilefrii – vasoconstrictor effect, thereby contributing to the elimination of edema of the mucous membranes of the nose, nasopharynx and paranasal sinuses, decrease in nasal discharge, resulting in nasal breathing easier. Pheniramine has anti-allergic and anti-edema effect, reduces the permeability of blood vessels, nasal discharge, lacrimation, eliminates sneezing. Ascorbic acid is involved in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration, in the synthesis of steroid hormones; increases the body's resistance to infections, reduces vascular permeability, It reduces the need for vitamins B1, IN 2, A, E, Folic acid, pantothenic acid. Improves tolerability of paracetamol and prolongs its action.

Testimony

Colds, flu, coryza, rinofaringit, sinusitis, inflammation of the paranasal sinuses, accompanied by fever, chills, nasmork, a feeling of nasal congestion, headache. Pain syndrome (mild to moderate severity): arthralgia, myalgia, neuralgia, migraine, toothache and headache, pain in trauma, algomenorrhea.

Contraindications

Hypersensitivity to paracetamol and other components, part of the drug; treatment with other drugs containing substances included in the fort Stopgripana; concomitant use of tricyclic antidepressants, ingiʙigorov monoaminooksidazы (MAO), beta-blockers; portal hypertension; alcoholism; diabetes; pregnancy, lactation; Children up to age 15 years.
Carefully: with advanced atherosclerosis of the coronary arteries, hypertension, definition, glucose-6-fosfatdegidrogenazы; blood diseases, congenital hyperbilirubinemia (Gilbert syndrome, Dubin-Johnson and Rotor), hepatic and / or renal failure, angle-closure glaucoma, prostate cancer; gipertireoze, pheochromocytoma, asthma.

Dosing and Administration

Contents 1 sachet (bag) Pour into a glass, pour hot water, Stir until dissolved and drink. Adults and children over 15 years: take one sachet 3-4 times a day with intervals between doses 6 hours (not more than 4 packets a day). Talk to your doctor, If symptoms do not resolve within 5 days.

Side effect

At therapeutic doses, the drug is generally well tolerated, However, there may be: high blood pressure, allergic reactions (itching, rash, hives, angioedema), dry mouth, NAUSEA, vomiting, pain in the area eiigastralnoy, decrease in the rate of psychomotor reactions, hypererethism, dizziness, heartbeat, sleep disturbance, urinary retention, počečnaâ how, glycosuria, midriaz, Parez akkomodacii, increased intraocular pressure. Given the presence of paracetamol in a preparation, rarely can be observed violations of the hematopoietic system (thrombocytopenia, leukopenia, agranulocytosis, gemoliticheskaya anemia, aplasticheskaya anemia); chronic administration of high doses – possible violations of the liver and kidneys (gepatoksicheskoe action nephrotoxicity – papillary necrosis).

Overdose

Due, usually, paracetamol. There are: pale skin, anorexia, nausea, vomiting, epigastric pain; in severe cases, liver failure, gepatonekroz, activity increase “Hepatic” transaminases, increased prothrombin time, encephalopathy and coma. The detailed clinical picture of liver damage manifested through 1-6 days. Rarely hepatic failure develops lightning speed and can be complicated by renal failure (tubular necrosis).
Treatment: gastric lavage, followed by the appointment of activated charcoal: simptomaticheskaya therapy; introduction of donators ditch SH-groups and precursors of glutathione synthesis – through methionine 8-9 hours after the overdose and N-acetylcysteine – through 12 no.
Interaction with other drugs
It enhances the effects of MAO inhibitors, sedatives, ethanol. Antidepressants, antiparkinsonian agents, antipsychotics, phenothiazine derivatives – increase the risk of urinary retention, dry mouth, constipation. Glucocorticoids increase the risk of elevated intraocular pressure.
Paracetamol reduces the effectiveness of uricosuric drugs and increases the efficiency of indirect anticoagulants.
Pheniramine concurrently with MAO inhibitors, furazolidone can lead to a hypertensive crisis, excitation, giperpireksii. Tricyclic antidepressants increase the sympathomimetic effects, co-administration of halothane increases the risk of ventricular arrhythmias. Reduces hypotensive effect of guanethidine, which in turn, It increases the activity of alpha-adrenostimuliruyushuyu phenylephrine. When concomitant administration with barbiturates Fort Stopgripana, difeninom, karʙamazepinom, rifampicin and other inducers of microsomal liver enzymes increased risk of hepatotoxicity of paracetamol.

Cautions

To avoid liver toxicity drug should not be combined with the use of alcoholic beverages.
If, despite taking Stopgripana Fort, disease is accompanied by continued fever or repetitive observed temperature increase, seek medical advice.

Effects on ability to drive and maintain vehicles moving mechanical equipment
Patients, Fort receiving Stopgripan, should refrain from activities, require attention and speed of mental and motor responses, including driving a car.

Product form

Powder for oral solution (lemon, blackcurrant). By 21,5 grams in sachets made of aluminum foil laminated paper. By 10 sachets together with instructions for use in paper cartons.

Storage conditions

In a dry place at a temperature above 25 ° C Keep out of reach of children.

Shelf life

2 year. Do not use beyond the expiration date, on the package.

Conditions of supply of pharmacies

Without a prescription.