Spiramycine

When ATH:
J01FA02

Characteristic.

Natural macrolide antibiotic.

Pharmacological action.
Antibacterial, bacteriostatic.

Application.

Lower respiratory infections ways (pneumonia, incl. atipichnaya, caused by the Legionella, mycoplasma, Chlamydia, exacerbation of chronic bronchitis), ENT (sinusitis, tonsillitis, otitis), bone and joints (osteomyelitis, arthritis), skin and soft tissue (mug, secondarily infected dermatitis, abscesses and cellulitis, incl. in dentistry), urinary tract (prostatitis, uretrit), gynecological and venereal (genital and extragenital clamidiosis, syphilis, gonorrhea, and a combination thereof), toxoplasmosis, incl. in pregnant women, prevention of acute articular rheumatism, and meningococcal meningitis (in persons, patients exposed to no more than 10 days prior to diagnosis), bacteriocarrier pertussis and diphtheria.

Contraindications.

Hypersensitivity, childhood (for in / injection), lactation.

Restrictions apply.

Obstruction of the bile ducts, hepatic failure.

Pregnancy and breast-feeding.

If necessary, may be used during pregnancy (spiramycin have not revealed teratogenic effects).

At the time of treatment must stop breastfeeding (spiramycin possible penetration into breast milk).

Side effects.

Nausea, vomiting, severity of epigastric, diarrhea, allergic skin reactions.

Dosing and Administration.

Inside, adult 6-9 million IU/day 2-3 reception, Children weighing more than 20 kg - 1,5 10 million IU/kg, 10-20 kg — 2-4 paketika granules on 0,75 ME million, to 10 kg-2-4 paketika granules on 0,375 ME million. Granules dissolved before use in water. In / infusion administered to adults only. In acute diseases bronholegochnykh-1.5-3 million IU every 8 no. The contents of the vial is dissolved in 4 ml of water for injection and give 100 ml 5% glucose during 1 no.