Natriya carbonate

When ATH:
B05CB04

Characteristic.

The white crystalline powder;, salt-alkaline taste. Stable in dry air, decomposes slowly in moist. Easily soluble in water (1:2) to form alkaline solutions (pH 5% solution 8,1), practically insoluble in ethanol. Molecular weight 84,01.

Pharmacological action.
Antacidnoe, mucolytic, expectorant, restores the alkaline condition of blood.

Application.

Gastric hyperacidity, gastric ulcer and duodenal ulcer, metabolic acidosis (incl. infections, intoksikatsiyah, diabetes, postoperatively), the need to liquefy bronchial secretions, inflammatory diseases of the eye, oral, the mucous membranes of the upper airways (incl. during stimulation of their acids); to loosen earwax; urine alkalinization; renal tubular acidosis, urate kidney stones, cystine kidney stones.

Contraindications.

Hypersensitivity; states, accompanied by the development of alkalosis; hypocalcemia (alkalosis and increased risk of tetanic seizures), chloropenia (loss of Cl^–, incl. induced vomiting or prolonged decline in the absorption in the gastrointestinal tract, It can lead to severe alkalosis).

Restrictions apply.

Swelling, arterial hypertension (condition may worsen), anuria or oliguria (increases the risk of excessive sodium retention).

Pregnancy and breast-feeding.

It is necessary to compare the risks and benefits, tk. Sodium bicarbonate can cause systemic alkalosis.

Category actions result in FDA - C. (The study of reproduction in animals has revealed adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not held, However, the potential benefits, associated with drugs in pregnant, may justify its use, in spite of the possible risk.)

Unknown, Does sodium bicarbonate gets into breast milk.

Side effects.

In the long-term use-alkalosis and its clinical manifestations: loss of appetite, nausea, vomiting, abdominal pain, anxiety, headache, in severe cases - tetanic spasms; may increase blood pressure; When using candles — poslablati effect, urge to defecate, diarrhea, flatulence, rumbling.

Cooperation.

With care combined with quinidine, simpatomimetikami.

Dosing and Administration.

Inside, I /, rectally (suppozitorii, enema), locally (in solution). As an antacid: inside, adults-0.5-1 g on several times a day, children-on 0.1-0.75 g per reception (depending on the age).

The candlelight appoint 0,3; 0,5; 0,7 g.

In/in drip- 1, 3, 4 or 5% solution.

When rhinitis, konayunktivite, Stomat, Baucis — in the form of poloskani, washings, inhalation of 0.5-2% solution; If acid on the skin and mucous recommended washing 2% solution.

For the correction of metabolic acidosis (infection, intoxication) injected inside or/in on-3 — azidoze 5 g (You can drip into the enema 4% solution), When expressed azidoze/in-on 50-100 ml of 3-5% solution (adult), When acutely developing azidoze — for 50-100 ml 8,4% solution.

In urology: inside, 3 g as an aqueous solution every 2 h until, until the pH of urine does not exceed 7,0; supporting dose is 5-10 g/d.

Precautions.

In case of clinical signs of alkalosis is necessary to make a break in the use of the drug.

When used for the correction of acidosis is necessary to control the acid-base balance.