Gilbert's syndrome – symptoms, diagnostics, Gilbert's syndrome treatment

Gilbert's syndrome – disturbance of conjugation (linking) Bilirubin is transmitted genetically. The disease is prevalent in males. The impetus for the development of the pathological process are usually transferred infection, especially viral hepatitis, genetically determined defects in liver enzyme system (deficiency of a specific enzyme glyukuroniltransferazy).

The main clinical symptom: occasionally jaundice, particularly intense expression on the sclera, growing under the influence of stress and decreases or disappears during the quiet period. There may be lethargy, weakness, aching pain in the right upper quadrant.

In a study of patients defined by enlargement of the liver; Biochemical studies reveal an increase in the blood levels of unconjugated (unrelated to protein) bilirubin, normal levels of liver enzymes (TOOLS, AsAT, alkaline phosphatase), that, along with the normal ultrasound of the liver eliminates viral hepatitis.

In favor of confirmation of the presence of Gilbert's syndrome shows a test with starvation: proven, after 24-48 hours of fasting blood concentration of the unconjugated bilirubin increases in 2 times.

The disease is prolonged, waves.

Gilbert's syndrome favorable forecast.

In a time of increased symptoms of jaundice recommended sparing regimen, invalid food, receiving sedatives, choleretic drugs.