SANORIN
Active material: Nafazolin
When ATH: R01AA08
CCF: Vasoconstrictor drugs for local application in an ENT-practice
ICD-10 codes (testimony): H10.2, H68, J00, J01, J04, J32, J37, R58, Z51.4
When CSF: 24.05.01
Manufacturer: IVAX Pharmaceuticals s.r.o. (Czech Republic)
Pharmaceutical form, composition and packaging
◊ Nasal drops 0.05% in the form of a transparent, colorless liquid.
| 1 ml | |
| Naphazoline nitrate | 500 g |
Excipients: boric acid, ethylenediamine, methylparaben, water.
10 ml – brown glass vials (1) with dropper – packs cardboard.
◊ Nasal drops 0.1% in the form of a transparent, colorless liquid.
| 1 ml | |
| Naphazoline nitrate | 1 mg |
Excipients: boric acid, ethylenediamine, methylparaben, water.
10 ml – brown glass vials (1) with dropper – packs cardboard.
◊ Spray nazalynыy 0.1% in the form of a transparent, colorless liquid, no visible particles, without smell.
| 1 ml | |
| Naphazoline nitrate | 1 mg |
Excipients: boric acid, ethylenediamine, methylparaben, Purified water.
10 ml – plastic bottles (1) with the dosing applicator and protective cap – packs cardboard.
Sanorin with eucalyptus oil
◊ Nasal drops 0.1% as a white, easily shake emulsion.
| 1 ml | |
| Naphazoline nitrate | 1 mg |
Excipients: ethylenediamine, boric acid, cetyl alcohol, methylparaben, eucalyptus oil, polysorbate 80, cholesterol, Liquid paraffin, Purified water.
10 ml – brown glass vials (1) with dropper “HEALTHY” and cap – packs cardboard.
Pharmacological action
Alpha2-adrenomimetik. When applied topically, has a rapid, pronounced and lasting vasoconstrictive action receptacle mucosa (reduces puffiness, hyperemia, exudation). Facilitates nasal breathing in rhinitis and reduces puffiness with conjunctivitis. Through 5-7 days there is tolerance.
Pharmacokinetics
The data on the pharmacokinetics Sanorin not provided.
Testimony
- Coryza;
- Sinusitis;
- Evstahiit;
- Laringit;
- To facilitate the rinoskopii;
- The need to stop nosebleeds;
- As an adjunct in the treatment of bacterial conjunctivitis (nasal drip 0.05%).
Dosage regimen
At acute rhinitis, Sinus, evstahiite, laryngopharyngeal, to facilitate the rinoskopii adult, older children and adolescents 15 years – by 1-3 nasal drops drops 0.1% or 1-3 dose nasal spray in each nostril 3-4 times / day; nasal drops 0.1% emulsion appoint 1-3 drops in each nostril 2-3 times / day.
Children over 2 years - By 1-2 nasal drops drops 0.05% in each nostril 2-3 times / day at intervals of not less than 4 no.
Use short: in Adult – no more 1 of the week, in children – no more 3 days. If nasal breathing easier, the use of the drug can be completed before Sanorin. Repeated use of the drug is possible in a few days.
At epistaxis It can be placed in the nasal passage cotton swab, wetted 0.05% solution preparation Sanorin.
IN an additional agent for treating bacterial conjunctivitis instilled into the conjunctival sac of nasal drops 0.05% by 1-2 drops 3-4 times / day.
Nasal drops in the form of an emulsion must be shaken before use. Open vial should be used within 4 weeks.
The first application is recommended to spray several times to press the dispensing device until a compact aerosol cloud. Before direct application, remove the protective cap, vial keep upright, terminal part of the dispensing device introduced into the nasal passage, then quickly and sharply to press the applicator. Immediately after the injection is recommended for easy inhale nose. After treatment applicator, close the protective cap.
Side effect
From the digestive system: nausea.
Cardio-vascular system: tachycardia, increased blood pressure.
CNS: headache, irritability.
Allergic reactions: rash.
Local reactions: reaktivnaя giperemiя, swelling of the mucosa of the nasal cavity; when using more 1 of the week – irritation, in some cases – rhinedema.
Contraindications
- Chronic rhinitis;
- Zakrыtougolynaya glaucoma;
- Arterial hypertension;
- Expressed atherosclerosis;
- Tachycardia;
- Thyrotoxicosis;
- Diabetes;
- Simultaneous reception of MAO inhibitors and the period up to 14 days after their application;
- Children up to age 2 years (nasal drops 0.05%);
- Children up to age 15 years (nasal drops 0.1% as solution and emulsion, spray nazalynыy);
- Hypersensitivity to the drug.
Pregnancy and lactation
Data on the safety of the drug during pregnancy and lactation (breast-feeding) not provided.
Cautions
With prolonged use of the severity of the vasoconstrictor action is gradually reduced (the phenomenon of tachyphylaxis), in connection with what is recommended by 5-7 days of treatment in adults and in 3 the day of the children to take a break for a few days.
The drug may cause resorptive effect.
The need of the drug Sanorin with other drugs the doctor determines individually.
Overdose
Symptoms: prolonged or frequent administration of the drug Sanorin the nasal cavity can cause swelling of the nasal mucosa and a feeling of stuffiness in his. The risk of overdose (especially in case of ingestion) Sanorin drug occurs in young children and can cause CNS depression, manifestations of which are somnolence, declination of fever, increased sweating, slowing heart rate, increased blood pressure or a subsequent reduction in, rarely – coma.
Treatment: removal of the drug, symptomatic therapy.
Drug Interactions
Simultaneous treatment with MAO inhibitors, and the period up to 14 days after their application, increases the risk of severe hypertension (release of catecholamines deposited under the nafazolina). Slows absorption of local anesthetics.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored out of reach of children, dark place at a temperature of 10 ° to 25 ° C. Shelf life - 4 year.
