RYNORUS

Published by
Vladimir Andreevich Didenko

Active material: Ksilometazolin
When ATH: R01AA07
CCF: Vasoconstrictor drugs for local application in an ENT-practice
ICD-10 codes (testimony): H66, J00, J01, J30.1, J30.3, J32, Z51.4
When CSF: 24.05.01
Manufacturer: Synthesis of (Russia)

Pharmaceutical form, composition and packaging

Nasal drops 0.05% as a clear, colorless or lightly colored liquid.

1 ml
Xylometazoline hydrochloride 500 g

Excipients: benzalkonium chloride, sodium chloride (Sodium chloride), disodium edetate (disodium эdetat), sodium dihydrogen phosphate dihydrate (sodium dihydrogen phosphate dihydrate), sodium phosphate dibasic 12 water (sodium hydrogen phosphate dodecahydrate), eucalyptus leaf oil (Eucalyptus oil), water d / and.

5 мл – флакон-капельницы полиэтиленовые (1) – пачки картонные.
10 мл – флакон-капельницы полиэтиленовые (1) – пачки картонные.

Nasal drops 0.1% as a clear, colorless or lightly colored liquid.

1 ml
Xylometazoline hydrochloride 1 mg

Excipients: benzalkonium chloride, sodium chloride (Sodium chloride), disodium edetate (disodium эdetat), sodium dihydrogen phosphate dihydrate (sodium dihydrogen phosphate dihydrate), sodium phosphate dibasic 12 water (sodium hydrogen phosphate dodecahydrate), eucalyptus leaf oil (Eucalyptus oil), water d / and.

5 мл – флакон-капельницы полиэтиленовые (1) – пачки картонные.
10 мл – флакон-капельницы полиэтиленовые (1) – пачки картонные.

Pharmacological action

Vasoconstrictor drugs for local application in an ENT-practice. Xylometazoline is an alpha-agonists, It causes constriction of the blood vessels of the nasal mucosa, eliminating its edema and hyperemia, restores patency of nasal passages, facilitates nasal breathing.

Effect of the drug occurs within minutes after application and lasts up 10 no.

Pharmacokinetics

When applied topically, the drug is practically not absorbed, therefore its concentration in blood plasma is very small (modern analytical methods not determined).

Testimony

- Acute respiratory infections with symptoms of rhinitis;

- Acute allergic rhinitis;

- Sinusitis;

- Otitis media (in a combination therapy to reduce the swelling of the mucous nasopharynx);

- To facilitate the rinoskopii.

Dosage regimen

Adults and children over 6 years eyedrops, nasal 0.1% by 2-3 drops in each nostril 3-4 times / day.

Children from 2 to 6 years eyedrops, nasal 0.05% by 1-2 drops in each nostril 1-2 times / day. Do not apply more 3 time / day.

Продолжительность лечения – не более 3-5 days (nonstop).

Before using the product should unscrew the bottle and bury the nose by gently pressing the bottom of the bottle.

Side effect

Local reactions: at frequent and / or long-term use - irritation and / or dryness of the nasal mucosa, burning, paresthesia, chikhaniye, hypersecretion; rare - swelling of the nasal mucosa.

Systemic reactions: редко – рвота, headache, heartbeat, increased blood pressure, insomnia, blurred vision, depression (long-term use of high doses of).

Contraindications

- Arterial hypertension;

- Tachycardia;

- Expressed atherosclerosis;

- Glaucoma;

- Atrophic rhinitis;

- Hyperthyroidism;

- Surgical interventions in the meninges (history);

- Pregnancy;

- Children up to age 6 years (nasal drip 0.1%);

- Children up to age 2 years (nasal drip 0.05%);

- Hypersensitivity to xylometazoline.

Do not use in the treatment of MAO inhibitors and tricyclic antidepressants.

FROM caution should be prescribed for patients with diabetes, CHD, angina III-IV functional class, prostatic hyperplasia, lactation.

Pregnancy and lactation

The drug Rinorus® contraindicated during pregnancy.

During breastfeeding drug should be used with caution.

Cautions

Do not use Rinorus® for a long time, eg, in chronic rhinitis.

Effects on ability to drive vehicles and management mechanisms

The dosages, exceeding recommended, It may affect the ability to drive a vehicle or equipment.

Overdose

Symptoms: increased side effects.

Treatment: symptomatic therapy.

Drug Interactions

Perhaps increased systemic effect of xylometazoline, while the use of MAO inhibitors and tricyclic antidepressants.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored in a dry, protected from light, reach of children, at a temperature from 15 ° to 25 ° C.. Shelf life - 2 year.

Published by
Vladimir Andreevich Didenko

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