Rifaksimin
When ATH:
A07AA11
Pharmacological action.
Antimicrobial.
Application.
Orally: bacterial intestinal infections (acute and chronic), diarrhea (Bacterial, travelers, year), prevention of infectious complications of gastrointestinal surgery (before- and postoperative), ammoniemia (in the complex therapy).
For topical application,: contagious impetigo, chafing, folliculitis, furunculosis, angular cheilitis, gidradenit, erythrasma, ecthyma and other bacterial skin infections.
Contraindications.
Hypersensitivity, ileus (full and partial), ulcerative lesions of intestine, pregnancy, natural infancy (to 2 years).
Side effects.
Nausea, vomiting, dyspepsia, allergic skin reactions (hives), skin irritation and the temperature rise in the area of application.
Dosing and Administration.
Dose picked individually depending on the type of pathogen and severity of the disease.
Inside, adults and children over 12 years: to 10-15 mg/kg/day, Children up to 12 years: on 20-30 mg/kg/day. Average duration of treatment is not more than 7 days. When diarrhea: adults and children over 12 years - 1 Table., children 6-12 years: Table 0.5-1., children 2-6 years: by 5 mL suspension every 6 no. Before and after the operation, when hyperammonemia: adults and children over 12 years - 2 Table., children 6-12 years are 1-2 table., children 2-6 years are 5-10 mL suspension every 12 no (Join ago- and postoperative prophylaxis) or via 8 no (when hyperammonemia).
Topically-applied on the skin area skin (without rubbing) a strip of ointment 2 to 10 see 2-4 times a day for 5 — maximum 15 days.
Cautions.
During prolonged treatment with high doses of, presence of ulcers of the intestinal mucosa urine becomes red-pink color.