Quetiapine

When ATH:
N05AH04

Pharmacological action.
Antipsychotic.

Application.

Acute and chronic psychosis, including schizophrenia.

Contraindications.

Hypersensitivity.

Application for Pregnancy and lactation.

Maybe, if the effect of therapy outweighs the potential risk to the fetus. At the time of treatment should stop breastfeeding.

Side effects.

Cardio-vascular system and blood (hematopoiesis, hemostasis): orthostatic hypotension, hypertension, tachycardia, leukopenia.

From the nervous system and sensory organs: drowsiness, dizziness, alarm, seldom-neirolepticeski Malignant Syndrome.

Metabolism: increase in cholesterol levels, serum triglycerides, ALT IS, changes in the level of liver enzymes.

On the part of the digestive tract: dry mouth, diarrhea or constipation, dyspepsia.

For the skin: rash, xerosis.

Other: pain syndrome (abdominal pain, headache, lower back, muscle, Chest, ear), asthenia, rhinitis, urinary tract infection, fever, weight gain.

Cooperation.

Tioridazin, inducers of cytochrome P450 (eg phenytoin) accelerate the biotransformation.

Overdose.

Symptoms: drowsiness, sedation, tachycardia, gipotenziya.

Treatment: symptomatic; restoration and control of the upper airway patency, ensuring adequate oxygenation and ventilation, monitoring and maintenance of the cardiovascular system.

Dosing and Administration.

Inside, 2 once a day. The daily dose is increased from 50 to 300 mg during the first 4 days (50, 100, 200, 300 mg) and further support within 300-750 mg per day depending on the clinical effect. Older patients and patients with liver and kidney initial dose of 25 mg followed by an increase of 25-50 mg per day to achieve an effective level of.

Precautions.

During treatment is recommended to refrain from using machinery and transportation Driving.