POSTERIZAN

Active material: inactivated microbial cells E. coli
When ATH: C05AX03
CCF: Preparation for topical use in diseases of the anorectal area
ICD-10 codes (testimony): I84, K60, L20.8, L29.3
When CSF: 27.01.03
Manufacturer: Dr. KADE Pharmaceutical Factory GmbH (Germany)

Pharmaceutical form, composition and packaging

Ointment for rectal and topical white with a yellowish tint, with a characteristic odor of phenol.

Excipients: Nipple, vaseline.

Preservative: phenol.

25 g – aluminum tuba (1) complete with an applicator – packs cardboard.

Rectal Suppositories white or white with a yellowish tint, with a characteristic odor of phenol.

Excipients: tallow, macrogolglycerol gidroksistearat.

Preservative: phenol.

5 PC. – blisters (2) – packs cardboard.

Pharmacological action

Preparation for topical use in diseases of the anorectal area

Posterizane antigens contained in the cell walls and the metabolites of E. coli in contact with mucous membranes of the rectum and skin anogenital increase local tissue resistance to the action of pathogenic microorganisms.

The drug stimulates the immune system T-, at the site of exposure increases the phagocytic activity of white blood cells and cells of the reticuloendothelial system, nonspecific immunity factors, reduces vascular exudation in inflammation, It normalizes the permeability and tone of blood vessels, It stimulates the regeneration of damaged tissues.

Pharmacokinetics

Data on the pharmacokinetics are not provided.

Testimony

The drug is prescribed for adults with the following diseases:

- Persistent for hemorrhoids;

- Perianal dermatitis;

- Anal and genital itching, particularly when resistance to treatment with other drugs;

- Anal fissure;

- Anopapillit.

Dosage regimen

The ointment should be applied thinly to the affected area of ​​the skin and mucous membranes in the morning and evening, and after each act of defecation. For a deeper introduction of ointment into the anus can be used screw applicator, supplied with the kit.

Suppositories are used for 1 PC. in the morning and in the evening, and after each act of defecation.

Perhaps the combined use of ointments and suppositories.

The duration of treatment is 2-3 of the week.

Side effect

Posterisan has no side effects even after prolonged use. As the preservative used in the preparation of phenol, therefore, possible allergic reactions in patients with hypersensitivity to this component. With the development of allergic reactions should discontinue use of the drug.

Contraindications

- Hypersensitivity to phenol.

Pregnancy and lactation

Can be used during pregnancy Posterisan indications.

Cautions

As a preservative used in the preparation of phenol.

Overdose

Currently, cases of drug overdose were reported Posterisan.

Drug Interactions

Drug Interactions drug Posterisan not described.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children, dry, dark place at a temperature no higher than 25 ° C; Do not freeze. Shelf life – 3 year.