Polizhinaks

Active material: Neomycin, Nystatin, Polymyxin B
When ATH: G01AA51
CCF: Drug with antibacterial and antifungal effect for local use in Gynecology
ICD-10 codes (testimony): B37.3, N72, N76, Z29.2
When CSF: 06.05.04
Manufacturer: Laboratoire INNOTECH INTERNATIONAL (France)

Pharmaceutical form, composition and packaging

Vaginal capsules Soft, light beige color, Oval; contents of capsules – fluid homogeneous mass of yellow to Brown.

1 caps.
neomycin sulfate35 thousand IU
polymyxin B sulfate35 thousand IU
Nystatin100 thousand IU

Excipients: hydrogenated soybean oil, Tefoz 63®, Dimethicone 1000.

Ingredients of the capsule shell: gelatin, glycerol, Dimethicone 1000, Purified water.

6 PC. – blisters (1) – packs cardboard.
6 PC. – blisters (2) – packs cardboard.

 

Pharmacological action

Drug with antibacterial and antifungal effect for local use in Gynecology. It has bactericidal activity. Active against grampolaugitionah microorganisms: Staphylococcus aureus, Corynebacterium spp.; Gram-negative microorganisms: Enterococcus faecium, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Proteus vulgaris, Klebsiella pneumoniae, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Ureaplasma urealyticum. Provides fungicidal effect on pathogenic fungi, especially drojjepodobne mushrooms kind Candida albicans, Cryptococcus, Hystoplasma.

Improves trophic processes in mucous membrane vagina.

 

Pharmacokinetics

Is evenly distributed to the mucous membrane vagina, providing local bactericidal and fungicidal effect. There is absorbed from the surface of the mucous membrane vagina.

 

Testimony

Treatment of infectious and inflammatory diseases, caused by susceptible mikrooorganizmami:

is a nonspecific vaginitis;

-mycotic vaginitis;

- Mixed vaginitis;

— vulvowaginita;

— cervikovaginity.

Prevention of infectious and inflammatory diseases:

before the surgery in the genital area;

- Before and after the cervix diathermocoagulation;

the uterine diagnostic procedures;

— prior to delivery.

 

Dosage regimen

One capsule enter deeply into the vagina in the evening before bedtime. A course of treatment – 12 days. Prophylactic course – 6 days.

If you skip one or more doses of treatment should be resumed in the usual dose.

 

Side effect

There are: allergic reactions. With long-term use may systemic manifestation of side effects aminoglikozidov.

 

Contraindications

- Hypersensitivity to the drug.

 

Pregnancy and lactation

The patient should be informed, that we do not recommend the use of drugs in pregnancy without consulting a doctor.

The drug should be avoided during breastfeeding.

 

Cautions

Terms of use of the drug should be limited to prevent the formation of individual resistance to pathogens and the risk of reinfection.

With long-term use may systemic manifestation of side effects aminoglikozidov, increasing renal failure.

During treatment is not recommended to use caps and latex condoms.

Should not interrupt a course of treatment during menstruation.

The patient should be informed, that in the case of renal disease should consult a doctor.

 

Overdose

Currently, the cases of drug overdose Poližinaks were reported.

 

Drug Interactions

It is not recommended to use Poližinaks in conjunction with spermicide, tk. possible slowdown preparation.

 

Conditions of supply of pharmacies

The drug is released under the prescription.

 

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 1.5 year.

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