Pyrantel

Published by
Vladimir Andreevich Didenko

Active material: Pyrantel
When ATH: P02CC01
CCF: Worming medication
When CSF: 10.01
Manufacturer: Marvel LifeSciences Pvt.Ltd. (India)

Pharmaceutical form, composition and packaging

Suspension orally viscous, yellow color.

5 ml
pyrantel pamoate 725 mg,
which corresponds to the content of pyrantel 250 mg

Excipients: metilparagidroksiʙenzoat, propilparagidroksibenzoat, saxarin, sodium chloride, sodium citrate, sucrose, lemon acid, karmelloza, sorbitol (70% solution), polysorbate 80 (Tween 80), chocolate flavor, creamy flavor, Purified water.

5 мл – флаконы темного стекла (1) – пачки картонные.
10 мл – флаконы темного стекла (1) – пачки картонные.
15 мл – флаконы темного стекла (1) – пачки картонные.

Pills yellow color, kapsulovidnye, with Valium on one side.

1 tab.
pyrantel pamoate 725 mg,
which corresponds to the content of pyrantel 250 mg

Excipients: starch, gelatin, acacia gum, metilparagidroksiʙenzoat, propilparagidroksibenzoat, sodium carboxymethyl, talc, magnesium stearate, colloidal silicon dioxide (aэrosyl).

3 PC. – стрипы (1) – пачки картонные.

Pharmacological action

Worming medication, It causes neuromuscular blockade sensitive to it and provide the helminths exile without excitement and stimulation of migration of affected worms. In the lumen of the intestine is effective against mature and immature forms of sensitive helminths both sexes. Highly effective against invasions, caused by pinworms (Enterobius vermicularis), askaridami (Ascaris lumbricoides), ankylostomamy (Ancylostoma duodenale Necator americanus и), against pathogens trichuriasis (Trichostrongulus colubriformis Trichostrongulus orientalis). Moderately active against whipworm (Trichirus freshiura).

Testimony

Askaridoz, эnterobyoz, ankylostomoz, necatoriasis, tryhotsefalez.

Contraindications

Hypersensitivity, myasthenia (During treatment).C care. Pregnancy, lactation, hepatic failure, childhood (to 6 Months).

Side effects

Nausea, vomiting, diarrhea, decreased appetite, headache, dizziness, drowsiness or insomnia, skin rash, hives, повышение активности “печеночных” трансаминаз, hearing disorder, hallucinations, confusion, paresthesia, hyperthermia.

Dosing and Administration

When ascariasis and enterobioze, при смешанных инвазиях этими гельминтами – внутрь (suspension or tablets), single, After breakfast at the rate of 10 mg / kg. Adults and children over 12 years - 750 mg, body weight more 75 kg- 1 g. Children from 6 Months before 2 years - 125 mg, 2-6 years - 250 mg, 6-12 years - 500 mg. In order to avoid a repetition rate samoinvazii allowed through 3 weeks after the first dose. When hookworm, Combined necatoriasis ascaridosis or other. helminth combined lesions appointed within 3 days 10 mg / kg / day or for 2 дней – по 20 mg / kg / day. При изолированном аскаридозе – 5 mg / kg once. Tablets must be chewed before swallowing.

Cautions

After receiving a laxative pyrantel not appointed. When enterobioze should conduct simultaneous treatment of all persons living together. After completion of treatment is necessary to control study of feces for the presence of helminth eggs. A more effective at infecting 12 duodenal hookworm, than the American hookworm. In the presence of helminthic infestation in a family member or a group of persons, are closely related, therapy is recommended to all contact persons. Thorough cleaning of premises and cleaning clothes for the destruction of helminth eggs is prevention of reinfection.

Cooperation

It should not be administered simultaneously with piperazine (weakening of the action). Increasing the concentration of theophylline in plasma.
Published by
Vladimir Andreevich Didenko

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