Active material: Pyrantel
When ATH: P02CC01
CCF: Worming medication
When CSF: 10.01
Manufacturer: Marvel LifeSciences Pvt.Ltd. (India)
Pharmaceutical form, composition and packaging
Suspension orally viscous, yellow color.
| 5 ml |
| pyrantel pamoate | 725 mg, |
| which corresponds to the content of pyrantel | 250 mg |
Excipients: metilparagidroksiʙenzoat, propilparagidroksibenzoat, saxarin, sodium chloride, sodium citrate, sucrose, lemon acid, karmelloza, sorbitol (70% solution), polysorbate 80 (Tween 80), chocolate flavor, creamy flavor, Purified water.
5 ml – vials of dark glass (1) – packs cardboard.
10 ml – vials of dark glass (1) – packs cardboard.
15 ml – vials of dark glass (1) – packs cardboard.
Pills yellow color, kapsulovidnye, with Valium on one side.
| 1 tab. |
| pyrantel pamoate | 725 mg, |
| which corresponds to the content of pyrantel | 250 mg |
Excipients: starch, gelatin, acacia gum, metilparagidroksiʙenzoat, propilparagidroksibenzoat, sodium carboxymethyl, talc, magnesium stearate, colloidal silicon dioxide (aэrosyl).
3 PC. – strips (1) – packs cardboard.
Pharmacological action
Worming medication, It causes neuromuscular blockade sensitive to it and provide the helminths exile without excitement and stimulation of migration of affected worms. In the lumen of the intestine is effective against mature and immature forms of sensitive helminths both sexes. Highly effective against invasions, caused by pinworms (Enterobius vermicularis), askaridami (Ascaris lumbricoides), ankylostomamy (Ancylostoma duodenale Necator americanus и), against pathogens trichuriasis (Trichostrongulus colubriformis Trichostrongulus orientalis). Moderately active against whipworm (Trichirus freshiura).
Testimony
Askaridoz, эnterobyoz, ankylostomoz, necatoriasis, tryhotsefalez.
Contraindications
Hypersensitivity, myasthenia (During treatment).C care. Pregnancy, lactation, hepatic failure, childhood (to 6 Months).
Side effects
Nausea, vomiting, diarrhea, decreased appetite, headache, dizziness, drowsiness or insomnia, skin rash, hives, activity increase “Hepatic” transaminases, hearing disorder, hallucinations, confusion, paresthesia, hyperthermia.
Dosing and Administration
When ascariasis and enterobioze, in mixed infestations by these worms – inside (suspension or tablets), single, After breakfast at the rate of 10 mg / kg. Adults and children over 12 years – 750 mg, body weight more 75 kg – 1 g. Children from 6 Months before 2 years – 125 mg, 2-6 years – 250 mg, 6-12 years – 500 mg. In order to avoid a repetition rate samoinvazii allowed through 3 weeks after the first dose. When hookworm, Combined necatoriasis ascaridosis or other. helminth combined lesions appointed within 3 days 10 mg / kg / day or for 2 days – by 20 mg / kg / day. The separate ascaridosis – 5 mg / kg once. Tablets must be chewed before swallowing.
Cautions
After receiving a laxative pyrantel not appointed. When enterobioze should conduct simultaneous treatment of all persons living together. After completion of treatment is necessary to control study of feces for the presence of helminth eggs. A more effective at infecting 12 duodenal hookworm, than the American hookworm. In the presence of helminthic infestation in a family member or a group of persons, are closely related, therapy is recommended to all contact persons. Thorough cleaning of premises and cleaning clothes for the destruction of helminth eggs is prevention of reinfection.
Cooperation
It should not be administered simultaneously with piperazine (weakening of the action). Increasing the concentration of theophylline in plasma.
