Acute leukemia plazmoblastnыy

A special feature of this form of leukemia is the ability of its constituent cells to produce abnormal immunoglobulins.

Plazmoblastny presented with acute leukemia in the bone marrow and blood mainly plazmoblastami, often different atypia, and non-differentiable from the blasts lacking cytoplasm basophilia, perhaps, relate to progenitor cells. And plasma cells are found in the blood; their content increased in the bone marrow. In the serum of patients found M-gradient due to a sharp increase in the production of monoclonal immunoglobulin leukemia cells.

The clinical picture of acute leukemia plazmoblastnogo

Acute leukemia plazmoblastnыy proceeds to the suppression of normal hematopoiesis germs, but often with the growth of leukemic foci vnekostnomozgovymi, with an increase in spleen, lymph nodes, liver. In one case of acute leukemia plazmoblastnogo observed in the final appearance of the disease in the skin leykemidov, leykemïçeskaya infiltration of the testicles, severe depression of normal hematopoiesis germs.

The clinical course, response to therapy with cytotoxic drugs, commonly used in acute leukemia, plazmoblastny leukemia is no different from other forms of acute lymphatic leukemia Nature, developing adult.