Odeston

Active material: Gimekromon
When ATH: A05AX02
CCF: The drug is a choleretic and antispasmodic action
ICD-10 codes (testimony): K59.0, K80, K81.1, K82.8, K83.0, K91.5, R11
When CSF: 11.14.03
Manufacturer: Pharmaceutical Works Polfa in Pabianice Joint-Stock Company (Poland)

Pharmaceutical form, composition and packaging

50 PC. – blisters (1) – packs cardboard.

Pharmacological action

The product with a pronounced antispasmodic and choleretic action. It has antispasmodic effect selectively on the biliary tract and sphincter of Oddi. The drug does not impair intestinal motility and reduces blood pressure. Providing choleretic effect, Odeston not only increases the amount of bile, but also increases the secretion of its components. It reduces stagnation of bile and prevents the deposition of cholesterol crystals.

Pharmacokinetics

Absorption

After ingestion is rapidly absorbed from the gastrointestinal tract. C_max in blood after oral administration is achieved by 2-3 no.

Deduction

T_1/2 is about 1 no. Report the news.

Testimony

- Biliary dyskinesia and sphincter of Oddi;

- Chronic cholecystitis and cholangitis;

- With biliary dyskinesia in patients with uncomplicated gallstone disease;

- States after operations on the gallbladder and biliary tract;

- Chronic constipation, nausea, vomiting, anorexia, caused by a decrease in bile secretion.

Dosage regimen

Adults appoint 200-400 mg (to 800 mg) 3 times / day for 30 minutes before meals for 2-3 weeks.

Babies administered according to the age of 200-600 mg / day, divided by 1-3 admission.

Side effect

Maybe: allergic reactions.

With prolonged use: diarrhea, flatulence, headache, abdominal pain, ulceration gastrointestinal mucosa.

Contraindications

- Obstruction of the biliary tract;

- Expressed human liver;

- Expressed by the human kidney;

- NYAK, Crohn's disease;

- Gastric ulcer and duodenal ulcer;

- Hemophilia.

Pregnancy and lactation

Application Odeston during pregnancy and lactation (breast-feeding) contraindicated.

Cautions

–

Overdose

Currently, cases of drug overdose were reported Odeston.

Drug Interactions

With simultaneous use of morphine reduces the effect Odeston.

In an application with metoclopramide Odeston notes relative weakening of the action.

Odeston increases effects of indirect anticoagulants.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored in a dry, dark place at a temperature no higher than 25 ° C. Shelf life – 3 year.