MYKOSPOR

Published by
Vladimir Andreevich Didenko

Active material: Bifonazol
When ATH: D01AC10
CCF: Antifungal agents for external use
When CSF: 08.02.01
Manufacturer: BAYER HealthCare AG (Germany)

DOSAGE FORM, COMPOSITION AND PACKING

Cream for external application 1% homogeneous, white.

1 g
bifonazole micronized 10 mg

Excipients: benzyl alcohol, cetostearyl alcohol, tsetylpalmytat, octyidodecanol, polysorbate 60, sorbitan stearate, Purified water.

15 г – тубы алюминиевые (1) – пачки картонные.

Pharmacological action

Antifungal broad spectrum. Effective fungicide for dermatophytes (tryhofyton, mykrosporum, epidermofiton); фунгистатически – на дрожжеподобные, molds (Aspergillus ferrus, Scopulariopsis brevicautus); Malassezia fufur. It is active against Corynebacterium minutissimum (IPC ranges from 0.5 to 2 ug / ml), Gram-positive cocci, except enterococci (IGC 4-16 ug / ml). Мишенью действия препарата является эргостерол – важнейший компонент мембраны грибов. Unlike other. It inhibits the synthesis of ergosterol imidazoles on 2 stages of its formation, which leads to structural and functional damage of the cell membrane of fungi. Минимальная эффективная концентрация – 5 ng / mL at least the duration of exposure 6 no; at concentrations 3 ng / ml inhibit the growth of rapidly proliferating mycelium Trichophyton mentagrophytes. In yeast fungi of the genus Candida has fungistatic, and concentrations 20 нг/мл – фунгицидное действие.

Testimony

Microsporia, trichophytosis smooth skin and scalp, crusted ringworm, ruʙrofitija, mycosis of the feet and hands, jock itch, pityriasis versicolor, erythrasma. The surface of the skin candidiasis, candidosis nail ridges, polish, genitals, interdigital intertrigo, hyperhidrosis stop. Onychomycosis.

Contraindications

Hypersensitivity (incl. on tsetilstearolu and lanolin).C care. Infants, pregnancy (I trimester).

Side effects

Hyperemia and skin irritation, burning sensation; local reactions at the edges or on the nail bed (irritation, hyperemia, maceration and peeling of the skin, contact dermatitis); allergic reactions.

Dosing and Administration

If it affects the smooth skin of hands, stop, large folds mushroom ointment applied thinly 1 once a day at night before bedtime, followed by rubbing in pockets. The duration of treatment depends on the pathogen, the size and location of the lesion. The solution is applied 1 once a day in the evening, before bedtime, a thin layer to the affected skin and rub. To plot the size of a palm is usually sufficient strip length cream 1 or 0.5 cm or a few drops of (about 3 drop). Продолжительность лечения при микозах стоп и межпальцевых промежутков стопы – 3 Sun; mycosis body, кистей и в складках кожи – 2-3 Sun; pityriasis versicolor, эритразме – 2 Sun; поверхностных кандидозах кожи – 2-4 Sun. The solution is suitable for the treatment of fungal infections of the scalp, and is applied to the pre-shaved lesion. A course of treatment - 4 Sun. After applying the solution bifonazole inflammation subsided and continue treatment cream, then apply powder. The course of treatment depends on the nature of the disease and is 2-5 Sun, при гипергидрозе стоп используют присыпку – 2-3 Sun. After the liquidation of clinical manifestations of mycosis treatment continues 10-15 days, applying cream, solution or powder 1 once a day for the prevention of relapse. The ointment or cream is applied to remove the nail onihomikozah simultaneously antifungal. The amount of drug, covering the entire affected nail, coated with a thin layer 1 once a day from the dispensing device. The nails of the fingers or toes after applying to them an ointment or cream should be closed and the adhesive bandage on 24 no. The dressing should be changed every day; wherein after removal of the dressing finger or toe to be omitted in warm water for 10 m. Thereafter, the softened nail infected tissue is removed with the scraper. The treated nail dried, it again applied the cream and covered with a ready to use plaster. Treatment is continued until, until the nail bed is smooth and will not remove all of the softening (about 7-14 days, depending on the size of the affected area and the thickness of the nail). The ointment or cream has an effect only on the affected part of the nail. If irritation occurs, the skin around the nail should be coated with zinc paste. For the treatment of small nail patch should be cut in half. After the nail is removed, therapy should be paste. Although clinically inflammation during treatment resolved quickly (itchy skin lesions to disappear 5 Day, воспалительные явления – к 12-13 Day, шелушение – к 13-14 Day Treatment), Treatment should continue for at least 3-4 Sun, to ensure the sanitation of foci of infection.

Cautions

In the absence or lack of effectiveness should further examine the patient (state immunity, blood, Endocrine, microcirculation of the affected area) and adjust the treatment in accordance with the results of the survey. The use in infants is only possible under the supervision of a physician. First 3 months of pregnancy is used only on strict conditions. The result of the treatment of onychomycosis depends on the thorough removal of the damaged part of the nail. Reusing the accompanying patches after contact with the cream can not be, it should be replaced, etc.. waterproof plaster, pre-sliced ​​properly.
Published by
Vladimir Andreevich Didenko

This site uses cookies and services to collect technical data from visitors to ensure performance and improve the quality of service.. By continuing to use our site, you automatically agree to the use of these technologies.

Read More