Methylthioninium chloride

When ATH:
V03AB17

Characteristic.

Dark green crystalline powder or dark green with bronze crystals shine. It is soluble in water (1:30), Aqueous solutions are blue. Slightly soluble ethanol, practically insoluble in ether and chloroform. Molecular weight 373,90.

Pharmacological action.
Antiseptic, detoxification.

Application.

Burns, pyoderma, folliculitis; infectious and inflammatory diseases of the urinary tract, incl. cystitis, uretrit; cyanide poisoning, carbon monoxide, hydrogen sulfide, metgemoglobinobrazuyuschimi poisons (nitritami, aniline and its derivatives), drug methemoglobinemia.

Contraindications.

Hypersensitivity.

Restrictions apply.

Pregnancy, lactation (when administered parenterally).

Side effects.

Allergic reactions; systemic effects: nausea, vomiting, abdominal pain, pain in the kidneys and bladder, headache, decreased appetite, mental discomfort.

Dosing and Administration.

B /, outwardly. As antiseptic: skin diseases-naruzhno 1% alcohol solution; with cystitis and urethritis — wash cavities aqueous solution 1:5000 (0,02%). As an antidote: when cyanide poisoning, carbon monoxide, hydrogen sulfide is in/in, very slow, 50-100 ml 1% aqueous; when poisoning metgemoglobinobrazujushhimi poison-in/, in small doses (0,1-0.15 ml 1% aqueous solution at 1 kg body weight).

Precautions.

Be wary appoint parenterally women of childbearing age. Do not enter n / a, intrathecal. Enter in / should be only very slowly (intermittently for several minutes).