Methyltestosterone

When ATH:
G03BA02

Characteristic.

A white or creamy white powder or crystals, hygroscopic. Practically insoluble in water, soluble in alcohols and organic solvents, slightly soluble vegetable oils.

Pharmacological action.
Androgenic.

Application.

Men: hypogonadotropic hypogonadism and primary, feminine physique and appearance of the boys in puberty, menopause in men; female: inoperable breast cancer in post-menopausal, in the postoperative period after radical surgical interventions for neoplastic processes in the breast in the premenopausal period.

Contraindications.

Hypersensitivity, breast tumor, prostate carcinoma, pregnancy, adolescence.

Pregnancy and breast-feeding.

Category actions result in FDA - X. (Animal tests or clinical trials revealed a violation of the fetus and / or there is evidence of the risk of adverse effects on the human fetus, obtained in research or practice; risk, associated with the use of drugs in pregnancy, greater than the potential benefits.)

Side effects.

Women: amenorrhea, virilization symptoms, girsutizm, acne rash; males: gynecomastia and oligospermia; swelling, dyspepsia, cholestatic hepatitis, gepatocellûlârnaâ cancer, hypercalcemia, increased bleeding, changes in libido, headache, anxiety, depression, generalized paresthesia, hyperlipidemia, allergic reactions.

Cooperation.

Proximity effect anticoagulants, insulin. The androgenic activity reduces barbiturates, cimetidine, paratireoidin.

Dosing and Administration.

Inside. Для мужчин доза составляет 10–40 мг 1 once a day, for 4-6 months. The highest daily dose - 100 mg. Для женщин при опухоли молочной железы доза — 200 mg 1 once a day (with careful observation of experts).