Methylergometrine

When ATH:
G02AB01

Characteristic.

Alkaloid sporыnьi. The white crystalline powder;. Slightly soluble in water and alcohol.

Pharmacological action.
Uterotoniziruyuschee.

Application.

Uterine bleeding: after manual removal of placenta, early postnatal, postoperative (cesarean section, removal of fibroids), post-abortion (incl. bloody issues); delayed involution of the uterus in the postpartum period, lohiometra.

Contraindications.

Hypersensitivity, pregnancy, 1-st and 2 nd stage of labor before the baby's head (tonic contraction of muscles of the uterus can cause fetal asphyxia).

Restrictions apply.

Arterial hypertension, CHD, mitral valve stenosis, occlusive vascular lesions, sepsis, pathology of the liver and kidneys.

Side effects.

Abdominal pain, nausea, vomiting, dizziness, headache, increased perspiration, increased blood pressure, tachycardia or bradycardia, reduced secretion of milk, allergic reactions: skin rash, anaphylactic shock, hypersensitivity pneumonitis. With long-term use or high sensitivity, a phenomenon ergotizma: vasoconstriction and malnutrition tissue (especially the extremities), mental disorders.

Cooperation.

It enhances the effects of sympathomimetic vasoconstrictor and ergotamine. The combination of dopamine contraindicated unnecessarily. may develop gangrene limb. Halothane reduces the sensitivity of the uterus and reduces the activity. Oxytocin increases the effectiveness of treatment and prevention of atonic uterine bleeding.

Overdose.

Symptoms: motor stimulation, convulsions, nausea, vomiting, diarrhea, epigastric pain, tachycardia, sensitivity disorders.

Treatment: carried out a set of measures, reinforcing and supporting the elimination of vital functions; No specific antidote.

Dosing and Administration.

Inside, / m and / in. Under the dose injecting a 0.1-0.2 mg (0,5Ml -1 0,2% solution), inside-1-2 table. 2-3 Times a day. Parenteral administration can be combined with oral. In atonicescom breeding bleeding- 0,2 mg in/m or 0.1-0.2 mg in/in, may reapply at intervals 2 no. In therapy subinvolution, lohiometry, postpartum hemorrhage is 0.125-0.25 mg inwards, or s /, in/m 0.1-0.2 mg to 3 once a day. With the active conduct of the second stage of labour is 0.1-0.2 mg in/in slowly after the appearance of the front of the shoulder, or immediately after the child (not later). Childbirth in conditions of general anesthesia — 0,2 mg. For caesarean section — after extracting the child in/in the 0.05-0.1 mg or/m 0,2 mg. Abortion, After the enlargement of the cervical canal is in/in 0.1-0.2 mg. In spontaneous abortion-in/0.05-0.1 mg.

Precautions.

It will be appreciated, that the application immediately after the child's birth (if the placenta is in the uterine cavity) may interfere with the separation of the placenta.