LIBEKSIN MUKO (Syrup)

Active material: Karʙoцistein
When ATH: R05CB03
CCF: Mucolytic drugs
When CSF: 12.02.01
Manufacturer: SANOFI-AVENTIS OTC (France)

Pharmaceutical form, composition and packaging

◊ Syrup brownish yellow to light brown, with the smell of rum and cinnamon.

[Ring] sucrose, metilparagidroksiʙenzoat, caramel coloring (powder, E150), cinnamon oil, aromatic elixir (ethanol, rom, aromaticheskaya supplement “rom”), Sodium hydroxide, Purified water.

125 ml – colorless glass vials (1) complete with a measured glass – packs cardboard.
200 ml – colorless glass vials (1) complete with a measured glass – packs cardboard.
300 ml – colorless glass vials (1) complete with a measured glass – packs cardboard.

DESCRIPTION OF ACTIVE SUBSTANCES

Pharmacological action

Mucolytic tool. Destroys disulfide bonds mucopolysaccharide and changes its ion charge, The resulting changes in the composition of bronchial secretions: reduces the number of neutral glycopeptides, increases sialoglikoproteidnaya function. It stimulates the motor function of the ciliated epithelium of the respiratory tract, It reduces viscosity and facilitates expectoration of bronchial secretions and discharge from the sinus.

Pharmacokinetics

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Testimony

Respiratory diseases, accompanied by the release of large amounts of viscous mucus: acute and chronic bronchitis, traheobronhit, bronchitis with BOS syndrome, bronchial asthma, pertussis, bronchiectasis; inflammatory diseases of the middle ear and sinus; preparing the patient for bronchoscopy and / or bronhografii.

Dosage regimen

Adults at intake at the beginning of treatment – by 750 mg 3 times / day; after the clinical effect – 1.5 g / day 3-4 admission.

Children aged 1 Months before 2.5 years – by 50 mg 2 times / day; aged 2.5 to 5 years – by 100 mg 2 times / day; senior 5 years – by 200-250 mg 3 times / day.

Side effect

From the digestive system: rarely – nausea, vomiting, epigastric pain, diarrhea, bleeding from the gastrointestinal tract.

Allergic reactions: rarely – skin rash, angioedema.

Contraindications

Gastric ulcer and duodenal ulcer in the acute phase, chronic glomerulonephritis in the acute phase, I trimester of pregnancy, Hypersensitivity to Karbotsistein.

Pregnancy and lactation

Contraindicated for use in the I trimester of pregnancy. To use caution in II and III trimesters of pregnancy and lactation (breast-feeding).

Cautions

To use caution in patients with a history of peptic ulcer disease.

Drug Interactions

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