Lanatoside C

When ATH:
C01AA06

Characteristic.

White or colorless crystalline powder. Very slightly soluble in water, it is difficult - in alcohol.

Pharmacological action.
Cardiac.

Application.

Acute and chronic circulatory insufficiency, tahiaritmicheskoy atrial fibrillation, paroxysmal tachycardia.

Contraindications.

Hypersensitivity, glikozidnaya intoxication.

Restrictions apply.

Vыrazhennaya bradycardia, OF блокада, paroxysmal ventricular tachycardia, subaortalnыy hypertrophic stenosis, yzolyrovannыy mytralnыy stenosis, acute myocardial infarction, unstable angina, WPW-syndrome, cardiac tamponade, arrythmia.

Side effects.

Anorexia, nausea, vomiting, diarrhea, arrhythmia, slowing AV conduction, drowsiness, confusion and delirium, reduced visual acuity, thrombocytopenia, skin rash.

Cooperation.

Calcium, catecholamines and diuretics increase the risk of glycoside intoxication. Quinidine, verapamil, nifedipine, spironolactone increase the concentration in the blood plasma. Antacids reduce the absorption in the gastrointestinal tract.

Overdose.

Symptoms: nausea, vomiting, bradycardia, arrythmia, ʙigeminija, blurred vision.

Treatment: potassium supplements, 2-4 grams per day, and antiarrhythmics 5% glucose solution with vitamins B₁, B₆, C.

Dosing and Administration.

Inside, I /. Dose set individually, depending on the clinical picture and individual susceptibility. To obtain a rapid effect introduced in / at 0.2-0.4 mg 1-2 times a day. Inside, taking since 0.25-0.5 mg 3-4 times a day. Maintenance dose - in / 0,4-0,2 mg, inside 0.5-0.25 mg. Higher doses: for adults inside - single 0,0005 g, daily 0,001 g, I / - single 0,0004 g, daily 0,0008 g.

Precautions.

It will be appreciated, that the likelihood of toxicity increases with hypokalemia, gipomagniemii, hypercalcemia, gipernatriemii, gipotireoze, marked dilatation of the heart cavities, pulmonary heart, miokardite.