Lactulose

When ATH:
A06AD11

Characteristic.

White powder, soluble in water. As impurities may contain galactose (no more 16%), laktozu (12%), epilaktozu (8%), fructose (1%).

Pharmacological action.
Stimulating peristalsis, laxative, hypoazotemic.

Application.

Constipation (incl. chronic); the need to soften the stool for medical purposes (hemorrhoids, need surgery on the colon and / or anal, pain after the removal of hemorrhoids, postoperatively); hepatic encephalopathy, including to whom and Preko (Treatment and Prevention); ammoniemia; intestinal dysbiosis; enteritis, by salmonella, şigellami, salmonellonositelstvo; putrid dyspepsia syndrome (in infants as a result of acute food poisoning).

Contraindications.

Hypersensitivity, galactosemia, bowel obstruction, rectal bleeding (the cause of which is not hemorrhoids), round- or ileostomy, suspected appendicitis.

Pregnancy and breast-feeding.

Category actions result in FDA - B. (The study of reproduction in animals revealed no risk of adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not done.)

Side effects.

Flatulence, diarrhea, abdominal pain, loss of electrolytes.

Cooperation.

Antibiotics (neomycin) and non-absorbable antacids reduce the effect of.

Overdose.

Symptoms: diarrhea, abdominal pain.

Treatment: the drug should be discontinued.

Dosing and Administration.

Inside. Dose set individually. When liver encephalopathy adults appoint up to 45-90 ml of syrup in 2-3 reception (up to 90-190 ml/day), for other indications — 15-45 mL/day. Children over 1 year 5-15 ml/day, younger 1 year - 5 ml / day.

Precautions.

To use caution in patients with diabetes (especially in the treatment of hepatic encephalopathy). When gastrocardiac syndrome should gradually increase the dose, to avoid flatulence; flatulence usually disappear on their own after 2-3 days of treatment. You can not assign to the background of abdominal pain, nausea and vomiting. When the diarrhea treatment cancel. Long-term treatment (more 6 Months) higher doses should regularly monitor the level of serum electrolytes.

Cooperation