Coldrex JUNIOR HotDrink

Active material: Vitamin C, Paracetamol, Phenylephrine
When ATH: N02BE51
CCF: The drug for the symptomatic treatment of acute respiratory diseases
ICD-10 codes (testimony): J06.9, J10, R50
At KFU: 03.02.01.03
Manufacturer: SmithKline Beecham S.A. (Spain)

Pharmaceutical form, composition and packaging

◊ Powder for oral solution (for children) heterogeneous, from white to pale yellow, lemon-scented; dissolved in 125 ml of hot water to form a hazy solution from yellow to yellow-green, having no foam on the surface, lemon-scented; there may be a slight precipitate.

Excipients: sodium saccharin, sodium cyclamate, lemon acid, sodium citrate, corn starch, sucrose, lemon flavor (610399IS), dye curcumin (E100), colloidal silicon dioxide.

3 g – bags (10) – packs cardboard.

Pharmacological action

Combined preparation for the symptomatic treatment of acute respiratory infections.

Paracetamol okazыvaet zharoponizhayushtee, analgesic effect.

Phenylephrine hydrochloride – sympathomimetic, It constricts blood vessels of the mucous membranes of the nose and paranasal sinuses, thereby reducing the swelling and nasal breathing easier.

Ascorbic acid compensates for the increased need for vitamin C for colds and flu.

Pharmacokinetics

The data on the pharmacokinetics Coldrex^® Junior HotDrink not provided.

Testimony

To eliminate symptoms of acute respiratory infections and influenza in children 6-12 years, including:

- Increased body temperature;

- Headache;

- Chills;

- Pain in joints and muscles;

- The feeling of nasal congestion;

- Pain in the sinuses and the throat.

Dosage regimen

Children aged 6 to 12 years appoint 1 Every sachet 4 no. Do not apply more 4 bags for 24 no. Do not exceed the indicated dose. The maximum duration of use - no more 5 days. If symptoms persist, requires medical consultation. The need for further treatment, the doctor determines the individual.

Contents 1 Pour the bag in a mug, pour about 125 ml of hot water, stir until dissolved. If necessary, Add cold water and sugar.

Side effect

Allergic reactions: rarely – skin rash, hives, angioedema.

From the hematopoietic system: rarely – thrombocytopenia, leukopenia, agranulocytosis.

Other: long-term use at doses, exceeding recommended, possible hepatotoxicity and nephrotoxicity.

Phenylephrine, part of the drug, It can cause nausea, Headache, a slight increase in blood pressure, rarely – heartbeat, which disappear after drug withdrawal.

At the recommended doses, the drug is generally well tolerated. When any adverse reactions should consult a doctor.

Contraindications

- Diseases of the blood system;

- Severe liver;

- Severe renal dysfunction;

- Thyrotoxicosis;

- Diabetes;

- Arterial hypertension;

- Heart disease (marked aortic stenosis, acute myocardial infarction, taxiaritmii);

- Zakrыtougolynaya glaucoma;

- Vrozhdennыy deficiency of glucose-6-fosfatdegidrogenazы;

- Children up to age 6 years;

- Simultaneously with other preparations, soderzhashtimi paracetamol;

- Hypersensitivity to the drug.

FROM caution use in patients with benign hyperbilirubinemia.

Cautions

To avoid liver toxicity Coldrex^® Junior HotDrink should not be combined with ethanol-containing drugs.

The need to use the drug in patients, giponatrievoy are on a diet doctor determines individually, since each bag Coldrex^® Junior contains HotDrink 60 mg of sodium.

The drug should not be taken concurrently with tricyclic antidepressants, beta-blockers, MAO inhibitors and for 14 days after their cancellation.

Active substances Coldrex^® Junior HotDrink not cause drowsiness.

Overdose

Symptoms: nausea, vomiting, stomachache, Sweating, pale skin, arrhythmia. Through 1-2 day possible symptoms of liver injury. In severe cases develop liver failure and coma.

In case of overdose (even if the child feels good) It should take into account the risk of delayed serious liver injury.

Treatment: for suspected poisoning should immediately seek medical advice. For the first 4 h shown poisoning gastric lavage. The specific antidote for poisoning by paracetamol – acetylcysteine.

Drug Interactions

The risk of hepatotoxicity is increased while taking barbiturates, difenina, karʙamazepina, rifampicin, AZT and other inducers of microsomal liver enzymes.

Metoclopramide and domperidone increase the rate of absorption of paracetamol, and cholestyramine reduces (the need for joint use with the drug Coldrex^® Junior HotDrink doctor determines individually).

Paracetamol reduces the effectiveness of diuretic drugs. Paracetamol at reception for a long time increases the effect of indirect anticoagulants (warfarin and other coumarin), which increases the risk of bleeding.

Phenylephrine reduce the hypotensive effect of guanethidine, guanethidine enhances alpha- adrenostimuliruyuschee effect of phenylephrine.

While the use of the drug Coldrex^® Junior HotDrink should be considered, that corticosteroids increase the risk of glaucoma; halothane increases the risk of ventricular arrhythmias.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 3 year.