XONDROKSID® (Pills)

Active material: Chondroitin sulfate
When ATH: M01AX25
CCF: Preparation, regulates the metabolism of the cartilage
ICD-10 codes (testimony): M15, M42
When CSF: 16.05.01
Manufacturer: NIZHFARM of (Russia)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

Pills on white with a yellowish tint to white with Valium a color shade, with splashes, risks and chamfer.

Excipients: calcium stearate, krospovydon, polyvinylpyrrolidone (povidone), microcrystalline cellulose, magnesium carbonate.

10 PC. – packings Valium planimetric (3) – packs cardboard.
10 PC. – packings Valium planimetric (5) – packs cardboard.
10 PC. – packings Valium planimetric (6) – packs cardboard.
10 PC. – packings Valium planimetric (9) – packs cardboard.
10 PC. – packings Valium planimetric (10) – packs cardboard.

Pharmacological action

Preparation, regulates the metabolism of the cartilage. Okazyvaet hondrostimuliruûŝee, regenerating and anti-inflammatory action.

Hondroksid^® It is involved in the construction of the basic substance of cartilage and bone. It affects the metabolic processes in hyaline and fibrocartilage. Slows down the process of degeneration of cartilage and connective tissue, inhibiting enzymes, cause cartilage damage.

Hondroksid^® It stimulates the biosynthesis of proteoglycans, promotes regeneration of the joint capsule and cartilage surfaces of the joints, increases the production of synovial fluid, reduces inflammation.

Could potentially interfere with the formation of fibrin clots in synovial and subchondral microvasculature.

Hondroksid^® slows the progression of osteoarthritis and degenerative disc disease, normalizes metabolism in hyaline tissue, It stimulates the regeneration processes in the articular cartilage. In applying the drug reduces pain and improves the mobility of the affected joints, wherein the therapeutic effect lasts for a long time after the end of therapy.

Pharmacokinetics

When a single oral dose of T sredneterapevticheskih_max Plasma is 3-4 no, T_max in the synovial fluid of 4-5 no.

Accumulating, mainly, cartilaginous cloth (T_max in articular cartilage is 48 no): synovium is no barrier to the penetration of the drug into the joint cavity. Excreted in the urine within 24 no.

Testimony

- The treatment and prevention of osteoarthritis, of osteochondrosis.

Dosage regimen

The drug is taken orally by 0.5 g (2 tab.) 2 times / day, with a little water.

The recommended duration of treatment is the initial 6 Months.

It should be taken into account, that the therapeutic effect is maintained for a 3-5 months after its cancellation depending on the location and severity.

If necessary, you can repeat courses of treatment, the duration of which is determined individually.

Side effect

In some cases,: allergic reactions, nausea, diarrhea.

Contraindications

- Pregnancy;

- Lactation;

- Hypersensitivity to the drug.

FROM caution use in patients with tendency to bleeding or the presence of.

Pregnancy and lactation

Do not use this drug during pregnancy and lactation.

Cautions

Special instructions to the drug is not provided.

Overdose

Data on overdose are not provided.

Drug Interactions

Intensifying the action of indirect anticoagulants, antiagregantov, fibrinolitikov, which requires more frequent monitoring of blood coagulation parameters while as applied to Hondroksidom^®.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored out of reach of children at temperature not exceeding 20 ° C. Shelf life – 2 year.