HONDROKSID (Gel for external use)

Active material: Chondroitin sulfate
When ATH: M02AX10
CCF: Preparation, regulates the metabolism of the cartilage
ICD-10 codes (testimony): M15, M42
When CSF: 16.05.01.02
Manufacturer: NIZHFARM of (Russia)

Pharmaceutical form, composition and packaging

Gel for external use yellowish, translucent, with a fruity odor.

1 g
Chondroitin sulfate50 mg

Excipients: dimethyl sulfoxide, propylene glycol, isopropanol, ethanol 95%, sodium bisulfite (sodium metabisulfite), nipagin, nipazol, Carbopol (karʙomer), orange flavor (identical to natural), Purified water.

20 g – aluminum tuba (1) – packs cardboard.
25 g – aluminum tuba (1) – packs cardboard.
30 g – aluminum tuba (1) – packs cardboard.
35 g – aluminum tuba (1) – packs cardboard.
40 g – aluminum tuba (1) – packs cardboard.

Ointment for external application light yellow wraparound dimethylsulfoxide.

1 g
Chondroitin sulfate50 mg

Excipients: dimethyl sulfoxide, Nipple byezvodnyi, vaseline, Purified water, distilled monoglycerides.

30 g – aluminum tuba (1) – packs cardboard.
50 g – aluminum tuba (1) – packs cardboard.

 

Pharmacological action

The drug to improve the regeneration of cartilage tissue and anti-inflammatory for outdoor use.

The stimulator of tissue regeneration.

Hondroksid® normalizes metabolism in hyaline tissue, It stimulates the regeneration (restoration) processes in articular cartilage, It has analgesic and anti-inflammatory action, slows the progression of osteoarthritis and degenerative disc disease.

The product contains natural ingredient chondroitin sulfate, derived from cartilage of cattle. It is a high mucopolysaccharide, which slows down the resorption of bone tissue and reduces the loss of calcium, improving calcium and phosphorus metabolism in cartilage, accelerates its repair, slows down the process of degeneration of cartilage. It prevents the collapse of the connective tissue. It inhibits the enzyme, cause cartilage damage, It stimulates the synthesis of glycosaminoglycans, promotes regeneration of the joint capsule and cartilage surfaces of the joints, increases the production of synovial fluid.

Dimethylsulfoxide promotes road Penetration chondroitin sulfate via kletočnye membrane vglubʹ Store. It has some anti-inflammatory, analgesic and fibrinolytic action.

Application Hondroksida® It reduces pain and increase mobility of the affected joints, as well as slow down the progression of osteoarthritis and degenerative disc disease.

 

Pharmacokinetics

The data on the pharmacokinetics Chondroxide® in the dosage form of a gel and ointment are not provided.

 

Testimony

- Treatment and prevention of osteoarthritis of peripheral joints and spine osteoarthritis.

 

Dosage regimen

Ointment or gel should be applied 2-3 times / day on the skin over the lesion. The ointment rubbed until completely absorbed within 2-3 m. The course of treatment is an ointment 2-3 of the week. The treatment gel is from 2-3 weeks before 2-3 months. If necessary, repeat the treatment.

 

Side effect

Maybe: allergic reactions.

 

Contraindications

- Hypersensitivity to the drug.

FROM caution should apply Chondroxide® in the dosage form of gel and pregnancy mazpri, lactation, in pediatric patients (efficacy and safety have not been established).

 

Pregnancy and lactation

With caution and after consulting a doctor should be applied Chondroxide® in the dosage form of a gel and ointment during pregnancy and lactation (breast-feeding).

 

Cautions

Avoid contact with the drug on the mucous membranes and open wounds.

Use in Pediatrics

With caution and after consulting a doctor should use the drug in children (efficacy and safety have not been established in pediatrics).

 

Overdose

Currently, cases of drug overdose Chondroxide® not reported.

 

Drug Interactions

Drug Interactions drug Chondroxide® not disclosed.

 

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

 

Conditions and terms

Ointment should be stored out of reach of children, dark place at a temperature of 2 ° to 20 ° C. Shelf life - 3 year.

The gel should be stored out of reach of children at or above 25 ° C. Shelf life – 2 year.

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