XONDROITIN-AKOS (Ointment for external application)

Active material: Chondroitin sulfate
When ATH: M02AX10
CCF: Preparation, stimulates the regeneration of cartilage tissue, with anti-inflammatory action
ICD-10 codes (testimony): M15, M42
When CSF: 16.05.01.02
Manufacturer: Synthesis of (Russia)

Pharmaceutical form, composition and packaging

◊ Ointment for external application light yellow, with the smell of dimethyl sulfoxide.

Excipients: dimethyl sulfoxide (100 mg / g), Nipple byezvodnyi, Vaseline medical, Purified water.

30 g – aluminum tuba (1) – packs cardboard.

Pharmacological action

Stimulator of cartilage tissue regeneration in joints (chondroprotector). Chondroitin sulfate is a high molecular weight mucopolysaccharide, which is obtained from the cartilage of the trachea of ​​cattle. It affects the metabolic processes in hyaline and fibrocartilage, reduces degenerative changes in the cartilage tissue of the joints, stimulates the biosynthesis of glycosaminoglycans in chondrocytes. Suppresses enzyme activity, causing damage to cartilage tissue, promotes regeneration of the joint capsule and cartilage surfaces of the joints, increases the production of synovial fluid. Improves calcium-phosphorus metabolism and reduces the loss of calcium in cartilage tissue, slows down bone resorption, normalizes metabolism in hyaline tissue, accelerates regeneration processes. Structurally close to heparin, prevents the formation of fibrin thrombi in the synovial and subchondral microvasculature. As a result of exposure, pain decreases and the mobility of the affected joints increases..

Dimethyl sulfoxide, part of the ointment, anti-inflammatory, analgesic and fibrinolytic action, promotes better penetration of chondroitin sulfate through cell membranes into tissues.

Chondroitin-AKOS ointment has analgesic and anti-inflammatory effects, normalizes metabolism and stimulates recovery processes in the tissues of the joints, leads to a decrease and disappearance of pain in the joints, an increase in joint mobility and a slowdown in the progression of osteoarthritis and osteochondrosis.

Pharmacokinetics

Data on the pharmacokinetics of the drug Chondroitin-AKOS are not provided..

Testimony

- treatment and prevention of osteochondrosis, osteoarthritis of the peripheral joints and spine.

Dosage regimen

Ointment is applied 2-3 times / day on the skin over the lesion and rubbed for 2-3 min until completely absorbed. Typically, the course of treatment ranges from 2-3 weeks before 2 months. If necessary, repeat the treatment.

Side effect

Rarely: allergic reactions.

Contraindications

- an acute inflammatory process in the area of ​​the wound at the site of the intended application of the ointment;

- widespread tissue necrosis;

- excess granulation, violation of the integrity of the skin at the site of the intended application of the ointment;

- Hypersensitivity to the drug.

Pregnancy and lactation

The need for the drug during pregnancy and lactation (breast-feeding) the doctor determines individually.

Cautions

With the development of allergic reactions the drug should be discontinued.

Avoid getting the ointment on mucous membranes and open wounds.

Use in Pediatrics

The doctor determines the need to use the drug in children individually..

Overdose

Currently, no cases of overdose of the drug Chondroitin-AKOS have been reported..

Drug Interactions

There were no cases of negative drug interactions when prescribing Chondroitin-AKOS ointment during therapy with other drugs, included in the conventional treatment regimens for degenerative diseases of the joints and spine.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children, dark place at a temperature of 2 ° to 20 ° C. Shelf life – 3 year.