Yodyksanol
When ATH:
V08AB09
Characteristic.
Iodine-containing water-soluble nonionic dimer (49,1%) connection.
Pharmacological action.
Rentgenocontrast.
Application.
Angiography: Cerebral, cardio-, Visceral, peripheral arterial disease- and venography; urography, X-ray computed tomography.
Contraindications.
Hypersensitivity (incl. to others. iodine-containing drugs); chronic renal, hepatic, heart failure decompensation, severe thyrotoxicosis, degidratatsiya, acute disorders of the liver and kidneys, pregnancy, lactation (after research suspended for 2 Nights), childhood.
Side effects.
The sensation of heat / cold with the introduction, nausea, vomiting, thromboembolism, allergic reactions (itch, hives, эritema, edema, anaphylaxis).
Overdose.
Manifested by nausea, vomiting, vascular collapse, impaired liver function, kidney.
Treatment: symptomatic; Hemodialysis is removed for 4 h to 50%.
Dosing and Administration.
Necessary breeding - 270–320 mg/ml - prepared in a physiological solution. For cerebral arteriography, 5-10 ml of solution is used, With aortography and urography - 40-60 ml, In computed tomography - 50-150 ml.
Precautions.
With a history of allergic diseases, asthma require premedication with antihistamines, gljukokortikoidami. Be wary appoint elderly and debilitated patients. The bottle can be opened only immediately prior to use, should carefully follow the procedure for the introduction of, often wash the catheter with saline (to reduce the risk of venous thromboembolism).
Cautions.
Availability iodixanol blood affects the results of laboratory tests for bilirubin, proteins, gland, Calcium, Phosphates, Copper.