INTETRIKS
Active material: Tilbrokhinol, Tilihinol
When ATH: P01A
CCF: With antibacterial drug, antiprotozoal and antifungal activity, derivative of 8-hydroxyquinoline. Antidiarrheal medication
At KFU: 06.19.02
Manufacturer: BEAUFOUR IPSEN INTERNATIONAL (France)
Pharmaceutical form, composition and packaging
◊ Capsules size №1, with an opaque dark red cap and opaque white body; contents of capsules – microcrystalline powder grayish yellow.
1 caps. | |
tilihinol | 50 mg * |
tilikhinol laurilsulifat | 50 mg * |
tilbrokhinol | 200 mg |
* – the total content in Tilihinol 1 caps. It is between 65.2 mg 72.2 mg (theoretically 68.7 mg ± 5%).
10 PC. – blisters (1) – packs cardboard.
10 PC. – blisters (2) – packs cardboard.
20 PC. – blisters (1) – packs cardboard.
Pharmacological action
Intestinal antiseptic broad spectrum. It has antimicrobial, antifungal and antiprotozoal action. It is active against gram-positive and gram-negative microorganisms, включая Vibrio cholerae; Entamoeba histolytica, Candida fungi. Unlike other. derivatives of 8-hydroxy-quinoline, It does not contain iodide ions in the structure or Cl-. Do not violate the balance saprophytic intestinal flora.
Testimony
Acute diarrhea of infectious origin (in the absence of suspicion of worm infestation), Chronic intestinal amebiasis (in combination with PM, acting on the tissue forms of amoebas), amebonositelstvo (luminal amoebae forms), prevention of diarrhea when visiting endemic regions, Travel.
Contraindications
Giperchuvstvitelnost.C caution. Hepatic or renal failure.
Side effects
Nausea, gastralgia.
Dosing and Administration
Inside. In acute intestinal infection severe – daily dose 6-8 capsules; multiplicity of purposes – 3-4 once a day. When to moderate disease – daily dose 4-6 capsules. A course of treatment – 3-5 days. In chronic amebiasis – by 4 capsules a day for 10 days; through 1 months, a second course of treatment. When diarrhea, caused by fungi, and for the prevention of fungal infections in the treatment of a broad spectrum antibiotic – by 3 capsules a day. For the prevention of intestinal infections when visiting endemic regions – by 2 capsules a day for a total residence time in endemic region. Take before meals with a little water. When assigning children can open the capsule and mix its contents with 1 tsp food.
Cautions
Do not appoint for a period exceeding 4 Sun. It should not be administered concurrently with other. hydroxyquinoline derivatives.