Interstitial nephritis – treatment of disease. Symptoms and prevention of the disease interstitial nephritis

Интерстициальный нефрит – что это за болезнь? Interstitial nephritis is a pathological process, characterized by acute or chronic inflammatory process in the interstitial tissue and renal tubule.

When this inflammation process does not apply to cups and kidney lohanki, and the pathological process is not accompanied by destructive changes in renal tissue.

The disease can develop at any age, but the most common pathology register persons in the age category 20-50 years.

Интерстициальный нефрит – Причины возникновения

Causes of tubulointersticial'nogo development of jade can be:

• taking some medicines, especially the antibiotic penicillin, non-steroidal anti-inflammatory drugs and diuretics;
• radiation;
• toxicity toxic substances;
• infectious diseases;
• diseases of connective tissues (systemic lupus erythematosus, scleroderma);
• obstruction of the urinary tract (stones, tumors, etc.).

Symptoms of interstitial nephritis

Specific symptoms of interstitial nephritis did not exist. Often accompanied by pathology symptoms such, as:

• generalized weakness, high perspiration;
• fever;
• headache, chills;
• drowsiness;
• body aches;
• pain in the lumbar region;
• nausea, loss of appetite;
• high blood pressure;
• increased urine formation;
• a sharp reduction in urine (in severe cases).

Интерстициальный нефрит – Диагностика

Diagnosis of the disease includes:

• analysis of the complaints of the patient and the medical history of the disease;
• general blood analysis;
• biochemical analysis of urine;
• sample Zimnickogo;
• sample Roberga;
• serological studies;
• definition of specific mikroglobulinov in urine;
• urine culture at the determination of bacteria;
• ultrasonography;
• Kidney biopsy;
• other research methods (at the discretion of the physician).

Интерстициальный нефрит – Виды заболевания

Interstitial nephritis happens to the acute and chronic. The acute form of the disease is characterized by acute onset, high temperature, sometimes hematuria (the presence of impurity of blood in urine). In the most severe cases may develop acute renal failure. In the vast majority of cases, the prognosis in acute intersticial'nom nephritis favorable.

In chronic nephritis develops intersticial'nom fibrosis. This leads to the development of nephrosclerosis pathology with further development of chronic renal failure.

On the mechanism of development of interstitial nephritis happens to be primary and secondary. A primary interstitial nephritis develops without prior defeats of kidneys. Secondary interstitial nephritis appears on the background of some other renal or vnepochechnogo disease.

On the etiology of interstitial nephritis happens to be toxic-allergic, postinfekcionnym, Autoimmune and idiopathic.

Интерстициальный нефрит – Действия пациента

If you suspect the presence of jade tubulointersticial'nogo need to see a doctor-urologist.

Treatment of interstitial nephritis

Given the fact, that tubulointerstitial nephritis often develops against the backdrop of the admission of certain medications, the basic principle of treatment is to identify and complete cessation medications. If in this case there is no therapeutic effect, the patient is assigned the gljukokortikosteroidnye drugs. The patient should ensure adequate hydration.

With the development of acute renal failure hemodialysis is conducted.

In chronic form of tubulointersticial'nogo nephritis the patient shall be appointed preparations, improve Microcirculation in the kidneys. In some cases showed hormonal drugs. The patient should observe the copious drinking regime and diet, rich in b vitamins.

Интерстициальный нефрит – Осложнения

• Development of chronic interstitial nephritis.
• Development of acute or chronic renal failure.
• The development of arterial hypertension.

Интерстициальный нефрит – Профилактика интерстициального нефрита

• Heavy drinking.
• Waiver of prolonged use of drugs, potentially dangerous for kidneys.
• Regular urine.
• Rehabilitation of chronic hotbeds of infection.
• Pereohlazhdenij and avoidance of excessive physical exertion.