Chronic tubulointerstitial nephritis – treatment of disease. Symptoms and prevention of the disease Chronic tubulointerstitial nephritis

Хронический тубулоинтерстициальный нефрит – что это за болезнь? Chronic tubulointerstitial nephritis-disease, characterized by non-infectious inflammation interstitial tissue and kidney tubules.

The pathology does not cause destructive changes in renal tissues, and inflammation does not apply to cups and kidney lohanki. Tubulointerstitial nephritis can develop at any age (including infants and the elderly). The disease occurs most often in the age 20-50 years.

Хронический тубулоинтерстициальный нефрит – Причины возникновения

Causes of tubulointersticial'nogo development of jade can be:

• taking some medicines, especially the antibiotic penicillin, non-steroidal anti-inflammatory drugs and diuretics;
• toxicity toxic substances;
• radiation;
• infectious diseases;
• diseases of connective tissues (systemic lupus erythematosus, scleroderma);
• obstruction of the urinary tract.

Symptoms of tubulointersticial'nogo nephritis

Specific symptoms when tubulointersticial'nom nephritis not detected. The disease may be accompanied by fever, gematurieй (the presence of blood in urine), pain in the lower back. In chronic forms, there is the risk of fibrosis interstitial tissue, atrophy of the tubules of the kidneys. The disease can lead to the development of chronic renal failure.

Хронический тубулоинтерстициальный нефрит – Диагностика

Diagnosis of the disease includes:

• analysis of the complaints of the patient and the medical history of the disease;
• general blood analysis, general urine analysis, biochemical analysis of urine;
• sample Zimnickogo, sample Roberga;
• serological studies;
• definition of specific mikroglobulinov in urine;
• urine culture at the determination of bacteria;
• ultrasonography;
• Kidney biopsy;
• other research methods (at the discretion of the physician).

Хронический тубулоинтерстициальный нефрит – Классификация

Development mechanism to distinguish between primary and secondary tubulointerstitial nephritis. Primary tubulointerstitial nephritis develops independently without prior kidney pathology. Secondary form of the disease develops against the background of other kidney or nepochechnyh diseases.

Depending on the etiology of tubulointerstitial nephritis happens:

• toxic-allergic-occurs under the influence of drugs, as well as chemical and toxic substances;
• post-viral-arises from infection;
• Autoimmune-develops when the immune system violations;
• idiopathic-develops due to an unknown reason.

According to the clinical picture of chronic tubulointerstitial nephritis can be in such forms:

• the expanded form is characterized by the manifestation of all the clinical symptoms of the disease;
• severe form is characterized by pronounced manifestations of chronic renal failure;
• «abortivnaja» form-is characterized by the absence of anurii. In this form of functioning kidneys recovers quickly;
• «очаговая форма» – характеризуется слабой выраженностью клинических симптомов. This form of the disease is favorable for, the patient is recovering quickly.

Хронический тубулоинтерстициальный нефрит – Действия пациента

If you suspect the presence of jade tubulointersticial'nogo need to see a doctor-urologist.

Tubulointersticial'nogo treatment of jade

Given the fact, that tubulointerstitial nephritis often develops against the backdrop of the admission of certain medications, the basic principle of treatment is to identify and complete cessation medications. If in this case there is no therapeutic effect, the patient is assigned the gljukokortikosteroidnye drugs. The patient should ensure adequate hydration.

When initially chonic tubulointersticial'nogo jade assigned patient medications, improve Microcirculation in the kidneys. In some cases showed hormonal drugs. The patient should observe the copious drinking regime and diet, rich in b vitamins.

Хронический тубулоинтерстициальный нефрит – Осложнения

Most often complicated chronic tubulointerstitial nephritis the development of chronic renal failure and hypertension.

Prevention of tubulointersticial'nogo nephritis

• Heavy drinking.
• Waiver of prolonged use of drugs, potentially dangerous for kidneys.
• Regular urine.
• Rehabilitation of chronic hotbeds of infection.
• Pereohlazhdenij and avoidance of excessive physical exertion.