Chronic hepatitis – treatment of disease. Symptoms and prevention of the disease chronic hepatitis
Chronic hepatitis – What is this disease? Chronic hepatitis is an inflammatory disease of the liver Dystrophic, which is more than six months.
Chronic hepatitis – The cause of the
IN 50 % cases of acute viral hepatitis with inadequate therapy goes into chronic hepatitis (basically the hepatitis C). The cause of chronic hepatitis can also be long-term effects of toxic substances on the body (alcohol, salts of heavy metals, benzene, etc.). To the development of chronic hepatitis can cause long-term prescription medications (sedativnyh, tetracycline antibiotics, antihypertensive, cytostatic, TB, narcotic drugs). Besides, chronic hepatitis can be associated with metabolic disorders, Autoimmune processes.
Symptoms of chronic hepatitis
Palpation of the liver is enlarged in size, felt a dull pain. Due to the accumulation in the blood and tissues of bile acids occurs aetiology, These symptoms may appear as depressed mental state, irritability, insomnia. Characterized by decreased appetite, nausea, belching, flatulence, intolerance of fatty foods, alcohol, unstable chair, fatigue, decreased performance. Skin, Sclera become yellowish (jaundice). The "hepatic signs include dilated capillaries as asterisks on the cheeks, back, redness of the internal surfaces of the hands ("liver Palms"). May increase spleen.
Disturbed blood coagulation, that is evident nasal bleeding, easy emerging bruises. Pains in joints.
Chronic hepatitis – Diagnostics
- Biochemical blood analysis: characterized by increased bilirubin, liver enzymes.
- Ultrasound of the liver: signs of inflammation.
- For a more accurate diagnosis of liver biopsies carry out, that gives an opportunity to assess the severity of inflammation, determine the presence of fibrosis or cirrhosis, and sometimes it helps determine what hepatitis.
- Serological analysis of blood: detection of antibodies to the hepatitis b virus, FROM.
- Viral research: identification of the relevant virus.
- Immunological study: detection of antibodies to components of the hepatic cells.
Chronic hepatitis – Classification
Classification of chronic hepatitis (Los Angeles, 1994):
- drug-induced hepatitis;
- autoimmune hepatitis;
- chronic viral hepatitis c, IN, D;
- cholestatic hepatitis;
- chronic hepatitis unclear etiology.
On the jetiologicheskomu factor of chronic hepatitis is divided into:
- viral (IN, FROM, D, G, F, TiTi, SUN);
- toxic-allergic, toxic (gepatotropnye poisons, alcohol, medicines, radiological lesions);
- metabolic (gemoxromatoz, Wilson-Konovalov disease, A1-antitrypsin deficiency);
- nonspecific reactive hepatitis;
- idiopathic (Autoimmune, etc.);
- secondary biliary hepatitis with Cholestasis vnepechenochnom.
The activity process distinguish:
- inactive;
- Active (moderate, minor, expressed, pronounced degree);
- nekrotizirujushhaja form.
Chronic hepatitis – Actions of the patient
From the diet of patients with chronic hepatitis you must absolutely exclude alcohol. Forbidden salty, fried, smoked, refractory fats (fat). At the same time, fats have jelchegonne properties, Therefore, must be present in the diet (about 35%). It is better to replace animal fats vegetable.
There should be continuous monitoring by a doctor-hepatitis, gastroenterologist or therapist.
Treatment of chronic hepatitis
Treatment depends on the severity of disease and includes the following items:
- the removal of the causes of disease (the destruction of the virus, the excretion of toxic substances, etc.);
- restoration and maintenance of structures, the functions of the liver;
- special diet.
Impact on virus perform using non-specific regulatory proteins, providing the antifibrotic, immunomodulatory effects. When viral hepatitis (B) appoint IFN-ɑ, lamivudine.
To improve resistance to the effects of liver pathogenic factors, enhance regeneration processes apply hepatoprotectors (essentiale, гепабене, hofitol, geptal etc).
Chronic hepatitis – Complications
Without proper treatment develops cirrhosis. There is a high risk of developing cancer (gepatocellûlârnaâ cancer).
Prevention of chronic hepatitis
Prevention of chronic hepatitis is acute viral hepatitis prevention, timely treatment of acute hepatitis of any etiology, alcohol abuse, limit the number of drugs taken to a necessary minimum, caution when in contact with gepatotoksicskimi substances.