GLYUKOSTERIL

Active material: Dextrose
When ATH: B05BA03
CCF: Preparation for partial rehydration and parenteral nutrition
When CSF: 21.06.01
Manufacturer: FRESENIUS KABI GERMANY GmbH (Germany)

PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING

Solution for infusion 20% clear, colorless.

Excipients: hydrochloric acid 25% (to maintain the pH level), Sodium hydroxide (to maintain the pH level), water d / and.

250 ml – glass bottles (6) – cardboard boxes.
250 ml – glass bottles (10) – cardboard boxes.
500 ml – glass bottles (6) – cardboard boxes.
500 ml – glass bottles (10) – cardboard boxes.
1000 ml – glass bottles (6) – cardboard boxes.
1000 ml – glass bottles (10) – cardboard boxes.
250 ml – plastic bottles (10) – cardboard boxes.
250 ml – plastic bottles (20) – cardboard boxes.
500 ml – plastic bottles (10) – cardboard boxes.
500 ml – plastic bottles (20) – cardboard boxes.
1000 ml – plastic bottles (10) – cardboard boxes.
1000 ml – plastic bottles (20) – cardboard boxes.

DESCRIPTION OF ACTIVE SUBSTANCES.

Pharmacological action

Means for rehydration and detoxification.

Isotonic dextrose (5%) It is used to replenish the body fluid. Besides, it is a source of valuable nutrient, which is easy to digest. The metabolism of glucose in tissues allocated a significant amount of energy, necessary for the functioning of the body.

The on / in the introduction of hypertonic solutions (10%, 20%, 40%) increases the osmotic pressure of blood, enhanced flow of fluid from the tissues into the blood, increased metabolism, improves liver function antitoxic, enhanced contractile activity of the heart muscle, dilates blood vessels, increased diuresis.

Pharmacokinetics

Dextrose, entering the tissue, phosphorylated, transformed into glucose 6-phosphate, which is actively involved in many of the body's metabolic links. Report the news.

Testimony

Compensation for lack of carbohydrates in the body. Correction of dehydration due to vomiting, diarrhea, postoperatively. Dezintoksikatsionnaya infuzionnaya therapy. Collapse, shock (as a component of a variety of blood-substituting liquids and antishock). It is used to prepare solutions of drugs for i / v administration.

Dosage regimen

Dextrose solution is introduced into / in the drip. 5% solution: a maximum of 150 drops / min, the maximum daily dose for adults – 2 l; 10% solution: a maximum of 60 drops / min, the maximum daily dose for adults – 500 ml; 20% solution: a maximum of 40 drops / min; the maximum daily dose for adults – 300 ml; 40% solution: a maximum of 30 drops / min, the maximum daily dose for adults – 250 ml.

Side effect

Metabolism: possible violations of ion balance, giperglikemiâ.

Cardio-vascular system: gipervolemia, acute left ventricular failure.

Other: fever.

Local reactions: rarely – Local irritation, the development of infection, tromboflebit.

Contraindications

Giperglikemiâ, diabetes, giperlaktatsidemiya, gipergidratatsiya, postoperative disorders of glucose utilization; circulatory disorders, threatening swelling of the brain and lungs; swelling of the brain, pulmonary edema, acute left ventricular failure, giperosmolyarnaya coma.

Pregnancy and lactation

Perhaps the use of dextrose during pregnancy and lactation (breast-feeding) on indications.

Cautions

Be wary appoint dextrose when decompensated heart failure, chronic renal failure (oligoanurii), giponatriemii.

To increase the osmolarity 5% Dextrose may be combined with an isotonic sodium chloride solution.

Drug Interactions

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