Glomerulonephritis – treatment of disease. Symptoms and prevention of the disease Glomerulonephritis

Glomerulonephritis – What is this disease? Glomerulonephritis – bilateral kidney, based on the damage of kidney clubockov. Kidney ball (glomerula) consists of numerous capillary loops, comprising a filter, through which the fluid passes from the blood into the renal tubular system. In case of renal filtration processes are violated clubockov. On the one hand through the damaged capillary walls into the urine begin to penetrate the blood cells, proteins and other blood components, so necessary for our organism. On the other hand the kidneys lose their ability to excrete water and toxic metabolic products.

Glomerulonephritis – It is a heterogeneous group of diseases. Allocate primary Glomerulonephritis, When the pathological process is limited to the kidney and secondary, When kidney damage is a consequence of any systemic diseases. Acute Glomerulonephritis has a duration of up to several weeks, Subacute to several months, chronic up to a year or more. Chronic Glomerulonephritis is one of the major causes of chronic renal failure, requiring hemodialysis and kidney transplantation.

Glomerulonephritis – Causes

  • infectious diseases, among which most often develops poststreptokokkovyj Glomerulonephritis, less likely to cause the disease can become other bacterial, viral and parasitic infections. The defeat mechanism is immune in nature and is not associated with direct action of the infective agents. Therefore, Glomerulonephritis usually develops within a few weeks after infection;
  • toxic factors (organic solvents, alcohol, drugs, mercury, some medications);
  • systemic diseases of different nature: lupus, periarteritis nodosa, Shenlejn disease – Genoha, Gudpaschera syndrome and other Vasculitis, amiloidoz;
  • hereditary syndromes with the defeat of kidneys: Al'porta syndrome, Fabry, etc.

Glomerulonephritis – Symptoms

Clinical signs of Glomerulonephritis are increased blood pressure, swelling, decrease the amount allocated for 24 hours urine (oligurija). With the emergence of such symptoms should seek immediate medical attention. Especially closely observe its state after streptococcal infections etiology (sore throat, Impetigo is a skin).

When urine laboratory studies reveal proteinuria (protein in urine) and gematuriju (blood in the urine) varying degrees of symptoms, cilindruriju. In serum kroviobnaruzhivaetsja desproteinemia (violation ratios of protein fractions), Sometimes the Hyperlipidemia and often giperazotemia.

Glomerulonephritis – Diagnostics

In diagnosis using biochemical analyses of blood and urine, definition of clubockova filtering and creatinine clearance, a blood test for antibodies antistreptokokkovye, x-rays, CT and ULTRASOUND EXAMINATION of abdominal cavity organs. Total number of cases to diagnose kidney biopsy is required.

Glomerulonephritis – Treatment

When pronounced clinical picture of the patient hospitalized, prescribed strict bed rest and diet for patients with kidney diseases. Drug therapy may include antibacterial, immunosupressivnuju and symptomatic therapy. In some cases, a kidney dialysis.

Glomerulonephritis – Prevention

Prevention of poststreptococcal Glomerulonephritis is the timely and proper antibiotic therapy in infectious diseases streptococcal etiology (Angina and skin lesions). Prevention of glomerulonephritis with other infectious processes is adequate treatment of relevant infectious diseases.

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