Gliquidone

When ATH:
A10BB08

Characteristic.

The white crystalline powder. Insoluble in water, bad - in alcohol.

Pharmacological action.
Hypoglycemic.

Application.

Diabetes mellitus type 2 in patients with middle and old age if you can not only compensate for glycemic diet.

Contraindications.

Hypersensitivity (incl. a sulfanyl- and etc. sulьfonamidam); prekomatosnoe and coma; diabetes, complicated by acidosis and ketoacidosis; diabetes mellitus type 1; Pregnancy and breast-feeding.

Pregnancy and breast-feeding.

Contraindicated. At the time of treatment should stop breastfeeding.

Side effects.

Metabolism: rarely - hypoglycemia.

From the digestive tract: rare - loss of appetite, nausea, vomiting, dyspepsia.

Other: seldom - a headache, allergic skin reactions (dermatitis), itch, leukopenia, thrombocytopenia.

Cooperation.

Effect increase phenylbutazone, chloramphenicol, tetracikliny, coumarin derivatives, cyclophosphamide, sulfonamides, MAO inhibitors, thiazide diuretics, beta-blockers, salicilaty, alcohol, weakening - oral contraceptives, chlorpromazine, sympathomimetic, corticosteroids, thyroid hormones, preparations, containing nicotinic acid. Compatible with biguanidami.

Overdose.

Symptoms: gipoglikemiâ.

Treatment: intake of sugar (better glucose), if necessary - in / or on / in a drip glucose solution.

Dosing and Administration.

Inside, before eating, at an initial dose 15 mg dose (morning); then gradually increase the dose (no more 120 mg / day) and the multiplicity of reception (optionally up 3 time).

Precautions.

During treatment, mandatory monitoring of blood glucose and urine, diet. Skipping meals or excess doses can lead to a pronounced hypoglycemic effect. When surgery, infections, accompanied by a high fever, it may be necessary to temporarily transfer the patient to an insulin. In severe kidney failure require constant medical supervision. Keep in mind the possibility of lowering the tolerance to alcohol.

Cautions.

In the transition from the treatment of other oral anti-diabetic drugs of similar action on gliquidone the dose is determined by the degree of compensation of exchange.

Cooperation