Glatiramer acetate
When ATH:
L04AX13
Characteristic.
Acetate salt of synthetic polypeptides, formed by four natural amino acids (L-glutamic acid, L-аланином, L-тирозином и L-лизином); by chemical structure has similarities to myelin basic protein.
Pharmacological action.
Immunomodulatory.
Application.
Multiple sclerosis relapsing-remitting course.
Contraindications.
Hypersensitivity, incl. to mannitol.
Restrictions apply.
Pregnancy, lactation, childhood (Safety and efficacy of aged 18 years to be determined).
Pregnancy and breast-feeding.
Maybe, if the effect of therapy outweighs the potential risk to the fetus and child (adequate and well-controlled studies of the safety of use in pregnant and lactating women have not performed).
Category actions result in FDA - B. (The study of reproduction in animals revealed no risk of adverse effects on the fetus, and adequate and well-controlled studies in pregnant women have not done.)
Side effects.
Vasodilation, hyperemia, pain or heaviness in the chest, heartbeat, increased blood pressure, anxiety / anxiety, weakness, breathlessness, nausea, difficulty weight management, arthralgia, lymphadenopathy, hives (It occurs immediately after the injection approximately 10% cases, are their own and do not require special treatment).
Local reactions: soreness at the injection site, redness, edema, itch.
Cooperation.
Compatible with glucocorticoids.
Dosing and Administration.
P /, 20 mg 1 once daily at one and the same time. Treatment long.