GEPATROMBIN
Active material: Allantoin, Dexpanthenol, Heparin natriya
When ATH: C05BA53
CCF: Preparation with antitromboticheskim and improves tissue regeneration effect for external use
ICD-10 codes (testimony): I80, I83, I83.2, I89.1, M65, N61, T14, T14.0
When CSF: 29.07.01.03
Manufacturer: HEMOFARM A.D. (Serbia)
Pharmaceutical form, composition and packaging
◊ Gel for external use colorless, clear, with a characteristic odor.
| 100 g | |
| Heparin sodium | 30 000 ME |
| allantoin | 250 mg |
| dexpanthenol | 250 mg |
Excipients: karʙomer, levomenthol, disodium эdetat, trolamin, Pine needle oil , oil Scots pine needles, lemon oil, sorbitol, isopropanol, softigen 767 (makrogola-6-glicerilkaprilokaprat), polysorbate, Purified water.
40 g – aluminum tuba (1) – packs cardboard.
◊ Gel for external use colorless, clear, with a characteristic odor.
| 100 g | |
| Heparin sodium | 50 000 ME |
| allantoin | 250 mg |
| dexpanthenol | 250 mg |
Excipients: karʙomer 940, levomenthol, disodium эdetat, triethanolamine, oil Scots pine, Cedar oil, lemon essential oil, sorbitol 70% (noncrystallizing), isopropanol, softigen 767, polysorbate 80, Purified water.
40 g – aluminum tuba (1) – packs cardboard.
◊ Ointment for external application white, uniform, with a characteristic odor.
| 100 g | |
| Heparin sodium | 30 000 ME |
| allantoin | 300 mg |
| dexpanthenol | 400 mg |
Excipients: bronopol, karʙomer, microcrystalline wax, trisalkilmakrogola phosphate, levomenthol, Liquid paraffin, purcelinol, glycerides of fatty acids, disodium эdetat, trolamin, vaseline, Purified water.
40 g – aluminum tuba (1) – packs cardboard.
◊ Ointment for external application white, uniform, with a characteristic odor.
| 100 g | |
| Heparin sodium | 50 000 ME |
| allantoin | 300 mg |
| dexpanthenol | 400 mg |
Excipients: bronopol, karʙomer 934, lunacera m, hostafat KW-340-N, levomenthol, Liquid paraffin, purcelinol, tegin 515, disodium эdetat, triethanolamine, white petrolatum, Purified water.
40 g – aluminum tuba (1) – packs cardboard.
Pharmacological action
Combination drug with antithrombotic, anti-inflammatory and improves tissue regeneration effect for external use.
Heparin – anticoagulant of direct action. The local application of heparin inhibits blood clots, has anti-inflammatory and anti-edematous, uluchshaet local blood flow.
Allantoin okazyvaet anti-inflammatory action, stimulates metabolism processes in tissues and promotes cell proliferation.
Dexpantenol vsasyvanie uluchshaet heparin, stimulates granulation and epithelization.
Pharmacokinetics
After local applying on skin heparin relatively quickly penetrates the epidermis and accumulates in the upper layers of the skin. Actively communicates with skin proteins. Of fabrics stands out slow with a period of allocation of about 1 no. The drugs have a concentration of 10 IU/ml in the epidermis and 0.6 IU/ml, respectively in the skin.
Testimony
-thrombosis;
- Tromboflebit;
-varicose veins;
-trophic ulcers drumsticks (ointment);
- Sports injuries;
— Tenosynovitis;
— inflammatory infiltrates.
Dosage regimen
Whisker ointment length 5 see mark the affected areas 1-3 times / day.
At diseases of veins the drug is used in the form of casts with ointment.
At trophic ulcers ointment is applied in the form of a ring width of about 4 cm.
At zabolevanijah veins of lower extremities ointment nanosjat light massirujushhimi napravleniju movements from the bottom up, razovuju dose it is recommended to rub is not fully, and individual portions.
Gel put a thin layer on the skin, rubbing light toning movements upwards. In case of application of the gel trombozah and tromboflebitah massirovanie is not recommended.
Side effect
Allergic reactions: skin rash, dermahemia, hives, angioedema.
Contraindications
-infected skin lesions;
- Violation of the integrity of the skin (Gel);
- Hypersensitivity to the drug.
Pregnancy and lactation
Pregnancy and lactation (breast-feeding) Gepatrombina with the content of sodium heparin 300 U/1 g is possible in cases, when the expected benefit of therapy to the mother outweighs the potential risk to the fetus or infant.
Data on the application of Gepatrombina with the content of sodium heparin 500 U/1 g in pregnancy and lactation is not provided.
Cautions
Included in the other ingredients of the gel essential oils provide antimicrpobial and analgesic action.
Overdose
The drug overdose Gepatrombin not available.
Drug Interactions
The medication with drug Gepatrombin not available.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored out of reach of children at temperature from 15 ° to 25 ° C. Shelf life – 3 year.
