GEPABENE

Published by
Vladimir Andreevich Didenko

Active material: dry extract of the herb dymjanki drug, dry fruit extract Silybum spotted
When ATH: A05AX
CCF: Phytomedicine with hepatoprotective and choleretic action
ICD-10 codes (testimony): B18.1, B18.2, K70, K71, K73, K82.8, K91.5
When CSF: 11.14.03.01
Manufacturer: ratiopharm GmbH (Germany)

Pharmaceutical form, composition and packaging

Capsules hard gelatin, size 0, light brown; содержимое капсул – порошок от оранжево-коричневого до светло-коричневого цвета, with lighter inclusions.

1 caps.
dry extract of the herb dymjanki drug 275.1 mg,
the corresponding 4.13 fumarovyh mg of alkaloids in terms of proteolytic enzymes
dry fruit extract Silybum spotted 83.1 mg,
incl. Silymarin 50 mg
with content in it at least silibinin 22 mg

Excipients: microcrystalline cellulose, corn starch, talc, macrogol 6000, copolyvidonum, magnesium stearate, silicon dioxide.

Ingredients of the capsule shell: gelatin, iron oxide yellow, iron oxide red, iron oxide black, Titanium dioxide, Purified water.

10 PC. – упаковки ячейковые контурные (3) – пачки картонные.

Pharmacological action

Combined medication of plant origin.

Herb extract dymjanki drug, contains the alkaloid fumarin, normalizes the number of sekretiruemoj bile, relieves spasms of the gallbladder and bile ducts, facilitating the flow of bile into the intestine.

Dry extract of milk thistle fruit contains Silymarin, the hepatoprotective effect of acute and chronic poisonings, has an antioxidant effect due to bind free radicals and toxic substances in the liver tissue, has membranostabilizirujushhej activity, stimulates protein synthesis, contributes to the restoration of hepatocytes.

The drug normalizes liver function with various acute and chronic pathological conditions.

Pharmacokinetics

After intake of flavonoids, constituent of Silymarin, excreted mainly jelchew and exposed kishechno-pechenocna recycling.

Testimony

The drug used in the treatment of the following diseases:

-biliary dyskinesia (incl. After cholecystectomy);

- Chronic hepatitis;

-chronic toxic liver.

Dosage regimen

Adults the drug is prescribed an average of 1 caps. 3 times / day.

At night bolevom syndrome recommend advanced take yet 1 caps. before bedtime. If necessary, the daily dose can be increased up to 6 caps. (the maximum daily dose) in 3-4 admission.

Гепабене capsules should be taken with food, without chewing, with a little water.

Side effect

Maybe: allergic reactions.

Sometimes: laxative effect, increased diuresis.

Contraindications

-acute inflammatory diseases of the liver and biliary tract;

- Up to 18 years;

- Hypersensitivity to the drug.

Pregnancy and lactation

Application of Гепабене in pregnancy and lactation (breast-feeding) perhaps only the attending physician.

Cautions

During drug treatment patients are prescribed by a physician must be strictly adhered to a regime, diet, other medicinal appointment, refrain from drinking alcohol.

Overdose

So far, cases of drug overdose Гепабене were reported. In the case of an overdose should seek doctor.

Drug Interactions

Prescribed drug interaction drug Гепабене so far not described.

Conditions of supply of pharmacies

The drug is released under the prescription.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life - 5 years.

Published by
Vladimir Andreevich Didenko

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