GEKSALIZ
Active material: Biklotimol, Enoksolon, Lysozyme hydrochloride
When ATH: R02AA20
CCF: The preparation with antimicrobial and anti-inflammatory action for local application in an ENT-practice and stomatology
Codes ICD-10 (testimony): J02, J03, J04, J31, J35.0, J37, K05, K12
When CSF: 24.03
Manufacturer: Laboratoires Bouchara-RECORDATI (France)
Pharmaceutical form, composition and packaging
◊ Lozenges orange-yellow, round, chamfered, with lemon odor; possible impregnation orange or white color.
1 tab. | |
ʙiklotimol | 5 mg |
lysozyme hydrochloride | 5 mg |
enoksolon | 5 mg |
Excipients: lemon oil, citric acid monohydrate, orange yellow S (E110), magnesium stearate, gummiaraʙik, icing.
10 PC. – blisters (3) – packs cardboard.
Pharmacological action
Combination preparation for topical use with antimicrobial, antiviral and anti-inflammatory action.
Biklotimol – antiseptic. It is active against staphylococci, streptococci and corynebacteria, It has anti-inflammatory and local anesthetic. When applied topically, characterized by a long action.
Lysozyme – mucolytic enzyme polypeptide, has antimicrobial action. It is active against Gram-positive bacteria, Gram-negative microorganisms are less sensitive to lysozyme. Helps increase the activity of nonspecific factors of the body's defense, anti-inflammatory and mucolytic action. Lysozyme exhibits antiviral activity (forms complexes with virus). Refers to natural factors, the body's defense.
Enoksolon – complex triterpene, glycyrrhizic acid extracted from. Inhibits 11-beta hydroxysteroid, inaktiviruющuю cortisol. Anti-inflammatory, antimicrobial and antiviral effect.
Pharmacokinetics
Pharmacokinetic studies have not been conducted drug Geksaliz.
Testimony
For the topical treatment of infectious and inflammatory diseases of the oral mucosa, pharynx and larynx, caused by susceptible biklotimolu, lysozyme and enoksolonu microorganisms:
- Acute and chronic pharyngitis;
- Faringolaringit;
- Tonsillitis;
- State after tonsillectomy;
- Glossitis.
Dosage regimen
Adults appoint 1 tab. every 2 no. The maximum dose – 8 Table / day.
Children over 6 years appoint 1 tab. every 4 no.
The duration of treatment should not exceed 10 days.
Tablets need to dissolve until complete dissolution.
Side effect
Maybe: allergic reactions, superimposed infection; prolonged use (more 10 days) – dysbacteriosis oral proliferation risk of bacterial and fungal infections.
Contraindications
- Children up to age 6 years;
- Hypersensitivity to the drug.
Pregnancy and lactation
During pregnancy and lactation (breast-feeding) Geksaliz prescribed only under strict indications.
Cautions
In appointing the drug to patients with diabetes need to take into account the, what in 1 tablet contains 1.054 g sugar.
If during the 5 days therapeutic effect is weak or absent, should review the applied therapy.
Overdose
Currently, cases of drug overdose were reported Geksaliz.
Drug Interactions
Avoid concurrent use of other drugs for topical application in the oral cavity.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 2 year.