Galavit: instructions for using the medicine, structure, Contraindications

Active material: aminodigidroftalazindion sodium
When ATH: L03AX
CCF: Immunomodulatory drugs
Manufacturer: ЦSM MEDIKOR (Russia)

Composition Galavita

1 vial with powder for solution for injection contains:

Galavit - 0,1 g.

1 rectal suppository contains:
Galavit - 0,1 g;
Excipients.

Galavit: release form

Powder for solution for injection in vials, by 5 bottles in a carton.
Rectal suppositories in blisters, by 10 suppositories in a carton.

Galavit: pharmachologic effect

The drug is an immunomodulator with a pronounced anti-inflammatory effect. The mechanism of action of the drug Galavit linked to its ability to change functional and metabolic activity of macrophages. When the inflammatory process Galavit the drug reduces the increased activity of macrophages, It inhibits the synthesis of pro-inflammatory cytokines, including interleukin-1, tumor necrosis factor and atomic oxygen. By reducing the functions of macrophages giperaktivirovannyh drug controls the degree of cyclicality and inflammatory reactions, reduces toxicity, associated with inflammation.

The drug leads to an improvement of nonspecific resistance, by regulating macrophage function, synthesis and recovery functions antigens, reduce autoaggression. Galavit promotes restoration of T-lymphocytes, improves cellular immunity. The drug stimulates the phagocytosis and improves the microbicidal function of neutrophilic granulocytes. Due to the effect of neutrophilic granulocytes to the drug enhances the body's non-specific resistance to infectious diseases.

The drug is not metabolized in the body, excreted mainly in the urine. The half-life after injecting is from 15 to 30 minutes, After rectal administration of 60 to 70 minutes. Clinical drug effect continues for 72 hours after a single application.

Galavit: Indications for use

The drug is used in combination therapy for the correction of immunity in adults in conditions such:

• Acute and chronic diseases of the digestive tract, accompanied by severe intoxication and diarrhea, including infectious diseases of the gastrointestinal tract, nespetsificheskiy colitis, Crohn's disease, viral liver disease (in particular, viral hepatitis B and C.), gastroenteritis, liver disease, non-viral origin.
• Galavit also used in the treatment of ulcers of the stomach and duodenum.
• Acute respiratory infections, including bronchitis, pneumonia.
• Inflammatory diseases of the oral cavity.
• Infectious posttraumatic osteomyelitis.
• Erysipelas, furunculosis.
• Urogenital infections, cytomegalovirus infection, benign prostatic hyperplasia, urogenital chlamydiosis, Mikoplasmosis.
• Herpetic infections of different localization, including genital herpes.
• Inflammatory diseases, that have developed against the background of secondary immunodeficiency.

The drug is also used to prevent infections after surgery.

The drug is used in oncology and immunology immunocorrection for rehabilitation in various diseases, including breast cancer, stage III, lung cancer stage III.

Galavit: mode of application

The dose and duration of treatment depend on the nature of the disease and individual patient. The course of treatment and dose of the drug is prescribed by the attending physician.

Galavit: powder for solution for injection

The powder was dissolved in 2 ml water for injection or 0,9% sodium chloride. The solution is administered intramuscularly.
When infectious diseases of the digestive tract is usually administered at an initial dose 200 mg, further reduce the dose to 100 mg 2-3 times a day until complete disappearance of symptoms of intoxication. Usually enough 2-3 injections for relieving symptoms in the acute phase of the disease.
When infectious diseases of various localization is usually administered in an initial dose 200 mg. Further, the drug is administered by 100 mg 2-3 once a day. After the disappearance of the symptoms, if necessary, go to the maintenance dose 100 mg 2-3 day. The course of treatment is usually long and can be up to 25 injection.

When non-communicable diseases of the gastrointestinal tract and urinary tract are usually prescribed during the acute course of the disease 20 0mg 1 once a day. After a few days to pass the introduction 100 mg 1 once every 2-3 day. Depending on the nature of the disease course of treatment ranged from 15 to 25 injection.
Patients with uterine myoma is usually prescribed for 100 mg 1 once a day for 5 days, then go to introduce 100 mg 1 once every 2 days for 10 days, continue to impose on 100 mg 1 once every 2-3 day. The course of treatment depending on the disease from 15 to 25 injection.

Patients with benign prostatic hyperplasia is usually prescribed for 100 mg 1 once a day for 5 days, then go to introduce 100 mg 1 once every 2-3 day.
For the prevention of infectious complications after surgery is usually prescribed before and after surgery for 5 days 100 mg 1 once a day. Then impose on 100 mg every other day for 10 days. After the end of such a scheme is administered in a maintenance dose of the drug 100 mg every 72 o'clock. Common course of treatment is usually 15 injection.

In diseases of the skin, including, recurrent abrasions, generally administered by 100 mg 1 once a day for 5 days, then go to introduce 100 mg 1 once every 48 hours. Common course of treatment is 20 injection.
For the treatment of herpes infection is usually prescribed by the scheme 100 mg 1 once a day for 10 days, then go to introduce 100 mg 1 once every 48 hours. The total course of treatment 20 injection. It is also possible injection scheme 100 mg 1 once every 48 hours. The total course of treatment 15 to 20 injection.

For the treatment of chronic inflammatory processes, caused by immunodeficiency, usually prescribed for 100 mg 1 once every 72 hours or 100 mg 1 once a day for 5 days, then go to introduce 100 mg 1 once every 48-72 o'clock. The total course of treatment up 20 injection.
For correction of immunity in patients, with cancer, usually prescribed for 100 mg 1 once a day for 5 days, then go to introduce 100 mg 1 once every 3 day. The total course of treatment 20 to 30 injection.

Galavit: suppositories for rectal use

A preparation in the form of suppositories for rectal administration. Before using the product you must wash your hands thoroughly, suppository release from the shell and put into the rectum. Before using suppositories is recommended to empty the bowel. The dose and duration of treatment depend on the nature of the disease. 1 suppository formulation contains Galavit 0,1 g of active substance.
When infectious diseases of various localization is usually administered in an initial dose 0,2 g. Then impose on 0,1 g 2-3 twice a day until symptoms of the disease, after which the drug is administered in a dose of 0,1 g 1 once every 72 o'clock. Total course is to 25 suppozitoriev.

When non-communicable diseases of the gastrointestinal tract and urinary tract are usually given at an initial dose 0,2 g 1 once a day for 2 days, then move on to maintenance dose 0,1 g product 1 once every 72 o'clock. The total course dose of 15 to 25 suppozitoriev.
Patients with uterine myoma and benign prostatic hyperplasia is usually prescribed for 0,1 g product 1 once a day for 5 days. Then move on to the maintenance dose 0,1 g 1 once every 72 o'clock. Total course is to 20 suppozitoriev.

For the prevention of infectious complications after surgery is usually prescribed by the scheme before and after surgery are administered 0,1 g product 1 once a day for 5 days. Then move on to the introduction 0,1 g product 1 once every 2 days for 10 days, continue to impose on 0,1 g product 1 once every 72 o'clock. The total course dose is 15 suppozitoriev.
In diseases of the skin, including, recurrent abrasions, usually given at the beginning of treatment 0,1 g product 1 once a day for 5 days, then transferred to the introduction of 0,1 g product 1 once every 48 hours. The total course dose is 20 suppozitoriev.
For the treatment of herpes infection is usually prescribed for 0,1 g product 1 once a day for 10 days, continue to impose on 0,1 g product 1 once every 48 hours. Total course Dose 25 suppozitoriev.

For the treatment of chronic inflammatory processes, caused by immunodeficiency, depending on the severity of the disease designate 0,1 g product 1 once every 72 hours or 0,1 g product 1 once a day for 5 days, then go to introduce 0,1 g product 1 once every 48-72 o'clock. The total course dose is 20 suppozitoriev.
For correction of immunity in patients, with cancer, usually administered at an initial dose 0,1 g 1 once every 2 days for 10 days, then transferred to the introduction of 0,1 g product 1 once every 72 o'clock. Total course dose is 20 to 30 suppozitoriev.

Galavit: side effects

At the moment, messages about the development of any adverse effects with the drug have been reported Galavit.

Galavit: Contraindications

Individual hypersensitivity to the drug.
The drug is contraindicated in pregnancy and lactation.

Galavit: overdose

Currently reported drug overdose were reported.

Galavit: storage conditions

A preparation in the form of suppositories should be stored in dry, protected from direct sunlight at a temperature of 5 to 12 degrees Celsius.
The drug is in the form of powder for solution for injection should be stored in a dry, protected from direct sunlight at a temperature of 15 to 25 degrees Celsius.
Shelf life of the drug in the form of suppositories - 2 year.
Shelf-life of the drug in the form of powder for solution for injection - 4 year.