Gadodiamid

When ATH:
V08CA03

Characteristic.

Non-ionic compound. The aqueous solution contains 0,5 mmol (287 mg) gadolinium complex hydrate 1 ml. Osmolality - 789 mOsm / kg (what in 2,8 times higher osmolality plasma, toughness 1,4 (at 37 °C).

Pharmacological action.
Contrast.

Application.

Magnitno resonance imaging of the brain and spinal cord.

Contraindications.

Hypersensitivity, expressed by the human kidney (glomerular filtration rate of less than 30 ml / min), pregnancy, lactation (for some time after the test is stopped), childhood (to 6 Months).

Side effects.

Nausea, dry mouth, anorexia, belching, vomiting, abdominal pain, diarrhea; headache, drowsiness, anxiety, mental disorders, ataxia, ataxia, paresthesia, tremor, fits up to generalized seizures, visual impairment, perversion and loss of taste, dizziness, weakness, feeling tired; pain, incl. chest, artralgii, mialgii, discomfort with the sensation of heat or cold, fever, chills, redness of the face, Sweating, deep swoon, noise in ears, renal failure, skin bruising, livor; an allergic reaction is itchy, hives, erythematous rash, etc.. cutaneous manifestations of erythema type, sore throat, symptoms of cardiovascular disorders, anaphylactoid reactions, idiosyncrasy; asymptomatic changes in the level of serum iron (through 8-48 h after injection); in the injection-local pain, the feeling of compression.

Cooperation.

Pharmaceutically compatible with any other drugs.

Overdose.

Removed by hemodialysis.

Dosing and Administration.

B / spray, single. Adults with a body weight up to 100 kg and children from 6 Months - 0,2 mg / kg (0,1 mmol / kg), adults weighing 100 kg and more 20 ml. The study started in a few minutes after the introduction and finish within 1 no (no more). Subsequent or repeated studies performed after restoring a normal level of clearance.

Precautions.

The study should carry out the doctor, having experience with magnetic resonance contrast media. Use caution with anemia, especially sickle cell and hemolytic, gemoglobinopatiâh, renal insufficiency and / or liver, allergic reactions (incl. history). It should be taken into account, sometimes produced negative results, even in the presence of pathological processes (some types of differentiated cancers and inactive plaques in multiple sclerosis are not exposed to contrast enhancement). Possible data corruption colorimetric methods for the determination of calcium in the blood, iron and other electrolytes, Therefore it is not recommended to use them within 12-24 hours after application. Breast-feeding resume no earlier than 24 hours after the study. During the injection dose to avoid fragmentation of the. Within a few hours after the procedure carefully monitor the condition of the patient — there is a risk of developing severe complications (anaphylactic shock, convulsions and other.).

Cautions.

Do not use the solution to change its color or the presence of large particles.