FLEET phospho-SODA

Active material: sodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate
When ATH: A06AD10
CCF: Laxatives osmotic properties
ICD-10 codes (testimony): Z51.4
When CSF: 11.08.03
Manufacturer: E C De Witt & Co. Ltd. (Great Britain)

Pharmaceutical form, composition and packaging

◊ Oral solution clear, colorless, a ginger-lemon odor.

Excipients: glycerol 99%, sodium saccharin, Sodium benzoate (E211), flavor of ginger and lemon (ginger oil, alcohol, lemon oil, partially stabilized oil of lemon, lemon acid, water), Purified water.

45 ml – plastic bottles (2) – packs cardboard.

Pharmacological action

Laxatives osmotic properties.

The mechanism of action of the drug is based on the increase via osmotic water retention in the lumen of the small intestine. Accumulation of fluid in the ileum leads to increased motility and subsequent purification of the intestine.

Pharmacokinetics

The drug has only a local effect, therefore, pharmacokinetic studies are not considered necessary. Sodium phosphate is poorly absorbed from the gastrointestinal tract, However, a small absorption of sodium and phosphate occurs is dose-dependent.

Testimony

- Preparation for endoscopic or radiological examination of the colon;

- Preparation for surgery on the colon.

Dosage regimen

The drug is used in adults and adolescents over the age of 15 years. Correction dose for elderly patients is not required.

Start taking Fleet Phospho-soda should be a day, appointed prior to endoscopic or radiologic procedures. If the procedure is scheduled for a time before noon, it is recommended to follow the instructions for your morning destination. If the procedure is scheduled for afternoon, it is recommended to follow the instructions for the purpose of day.

Morning appointment

The day before the procedure

IN 7 h in the morning instead of breakfast at least one ` 1 cup “light liquid” (incl. freed from solids soups, fruit juices without pulp, tea and coffee, clear carbonated and non-carbonated soft drinks) or water.

The first dose should be taken immediately after breakfast. In half a glass (120 ml) Cold water should be dissolved contents 1 bottle (45 ml). Ready to drink and to wash down with a solution of one (or more) glass (240 ml) Cold water.

IN 13 h instead of dinner should drink at least 3 glasses (720 ml) “light liquid” or water.

IN 19 h instead of supper drink at least 1 cup “light liquid” or water.

The second dose should be taken immediately after dinner. In half a glass (120 ml) Cold water should dissolve the contents of the second vial (45 ml). Ready to drink and to wash down with a solution of one (or more) glass (240 ml) Cold water.

You may want to drink more fluids. “Light liquid” and water to drink until midnight.

Full-time appointment

The day before the procedure

IN 13 h during lunch can easily bite. After dinner, you can not eat any solid food.

IN 19 h instead of dinner should drink 1 glass “light liquid” or water. If you wish, you can drink more fluids.

The first dose should be taken immediately after dinner. In half a glass (120 ml) Cold water should dissolve the contents of the second vial (45 ml). Ready to drink and to wash down with a solution of one (or more) glass (240 ml) Cold water. If you wish, you can drink more fluids.

During the evening you need to drink at least 3 glasses “light liquid” or water.

Day procedure

IN 7 h in the morning instead of breakfast should drink 1 glass “light liquid” or water. If you wish, you can drink more fluids.

The second dose should be taken immediately after breakfast. In half a glass (120 ml) Cold water should dissolve the contents of the second vial (45 ml). Ready to drink and to wash down with a solution of one (or more) glass (240 ml) Cold water.

Water and “lighter fluid” You can use up to 8 hours.

Typically, the drug is a chair for half an hour to 6 no.

Side effect

From the digestive system: nausea, vomiting, stomach ache, abdominal distention, diarrhea; rarely – endoscopic mucosal sigmoid colon and rectum can be observed single or multiple aftopodobnye Education (clinically insignificant, spontaneously disappear without treatment).

CNS: asthenia, weakness, headache, dizziness.

Metabolism: in selected patients at risk – dehydration and / or electrolyte imbalance (incl. giperfosfatemiя, hypocalcemia, kaliopenia, gipernatriemiya, Acidosis).

Other: allergic reactions.

Contraindications

Do not use the drug in patients with the following diseases, states or suspicion on them:

- Partial or complete intestinal obstruction;

- Violation of the integrity of the intestine;

- Megacolon (congenital or acquired);

- Acute inflammatory bowel disease;

- Heart failure;

- Renal failure;

- The presence of nausea, vomiting, abdominal pain;

- Childhood and adolescence up 15 years;

- Hypersensitivity to the drug.

Pregnancy and lactation

Do not use Fleet Phospho-soda during pregnancy, because not enough reliable information on the ability of the drug toxic effect on the fetus and / or cause its formation.

Since sodium phosphate excreted in breast milk, should abandon breastfeeding immediately after the first dose and for the following 24 hours after the last dose.

Cautions

The drug should not be used as a means to treat constipation.

Precautions should use the drug in elderly patients, loose, with impaired renal function, heart disease, colostomy, We are on a diet low in salt, as there are likely to develop hyperphosphatemia, hypocalcemia, hypokalemia, against the background of dehydration hypernatremia, acidosis.

It should warn patients of a possible loose stools.

Very rarely endoscopic mucosal rectum and sigmoid observed single or multiple changes aftopodobnye: lymphoid follicles, Education discrete inflammatory, no change, caused by the conduct training. These abnormalities are not clinically significant and disappear spontaneously without treatment.

Occasionally there may be a lengthening of the QT interval on an electrocardiogram as a result of the type of electrolyte imbalance hypokalemia or hypocalcemia.

Effects on ability to drive vehicles and management mechanisms

The drug does not affect the ability to drive vehicles and management mechanisms.

Overdose

There are cases of death as a result of hyperphosphataemia with concomitant hypocalcaemia, hypernatremia and acidosis, after treatment with high doses of children and patients with constipation.

At the same time, there are cases of complete recovery after an accidental overdose of the drug in children or in patients with constipation (One of them was 6-fold dose of funds).

Drug Interactions

It should be used with caution on patients, host channel blockers kaltsievh, Diuretic, agents based on lithium and other drugs, able to influence the level of electrolytes, since there is a possibility of hyperphosphatemia, hypocalcemia, hypokalemia, against the background of dehydration hypernatremia, acidosis.

During ingestion of Fleet Phospho-soda may be a delay or discontinuation of drug absorption in the gastrointestinal tract. Action regularly take drugs (incl. antibiotics, oral contraceptives, antiepileptic and hypoglycemic agents) It may be reduced or absent.

Conditions of supply of pharmacies

The drug is resolved to application as an agent Valium holidays.

Conditions and terms

The drug should be stored out of reach of children at or above 25 ° C. Shelf life – 3 year.