Active material: deoxyribonucleat complex sodium iron
When ATH: J05AX
CCF: The antiviral and immunomodulatory drugs
ICD-10 codes (testimony): A60, A84, B00, B02, B18.2, B20, B24
At KFU: 09.01.05.03
Manufacturer: TEHNOMEDSERVIS ZAO FP (Russia)
The solution for the / m 15 mg / ml clear, yellow color, without foreign impurities.
| 1 ml | 1 fl. | |
| deoxyribonucleat complex sodium iron | 15 mg | 30 mg |
2 мл – флаконы (5) – упаковки ячейковые контурные (1) – пачки картонные.
The solution for the / m 15 mg / ml clear, yellow color, without foreign impurities.
| 1 ml | 1 fl. | |
| deoxyribonucleat complex sodium iron | 15 mg | 75 mg |
5 мл – флаконы (5) – упаковки ячейковые контурные (1) – пачки картонные.
The antiviral drug with a strong immunomodulatory effect of natural origin. It is a purified standardized deoxyribonucleat sodium salt complex with iron.
Exhibit antiviral action against RNA- and DNA viruses. The drug activates the antiviral, antifungal and antimicrobial immunity.
In exchange application Ferrovir in the complex therapy of HIV infection observed increase in CD4 lymphocytes in the blood (It persists for 1-1.5 months after the end of treatment). Simultaneously decreasing the viral load in the body, expressed in the reduction of HIV RNA level compared to baseline.
When recurrent herpes infection recurrence and shortened developing long-term remission after a 10-day treatment kursovovgo.
Application for chronic hepatitis C leads to a decrease in the replicative activity of the hepatitis C virus, and puts the process in a latent phase of the restoration of liver cells and the absence of viral replication, improves tolerability (decrease nausea, dizziness).
The product is characterized by a high degree of activity in the joint presence of viruses and the main opportunistic diseases.
Absorption
When i / m administration is rapidly absorbed into the blood. The time to reach Cmax – 0.5 no.
Distribution
Through 0.5 h the concentration of drug in the blood is reduced in connection with its distribution in the organs and tissues. Distributed in organs and tissues via endolymphatic transportation way; It has a high affinity for bodies of the hematopoietic system; It has been actively involved in cellular metabolism, embedding into cell structures. During the course of daily use of the property has cumulated in organs and tissues.
Deduction
T1/2 – 36 no. Среднее время удержания препарата в органах и тканях – 72 no. Excreted unaltered in the form of metabolites, преимущественно с мочой и частично – с калом.
Ferrovir used in a combination therapy:
- Chronic hepatitis C;
- Herpes;
- Tick-borne encephalitis;
- Viral opportunistic infections in HIV-positive patients;
- HIV-positive patients and AIDS patients;
- HIV-infected patients with hepatitis C;
- HIV-infected patients with recurrent herpes infection.
Adults at treatment of HIV infection or AIDS the drug is prescribed in / m 5 ml 2 times / day for 14 days. Последующие курсы – по показаниям.
At the treatment of herpes infections – в/м по 5 ml 1-2 times / day for 10 days.
At treating hepatitis C. – в/м по 5 ml 2 times / day for 14 days. In the following 14 дней – в той же суточной дозе через день.
At treatment of tick-borne encephalitis - By 5 ml 2 times / day for 5-10 days.
Maybe: temperature rise, hyperemia, moderate pain at the injection site.
- Pregnancy;
- Lactation (breast-feeding);
- Children's age;
- Hypersensitivity to the drug.
The drug is contraindicated during pregnancy and lactation (breast-feeding).
To reduce pain medication should be administered / m slowly over 1-2 m.
In / in the introduction of the drug is not permitted.
Clinical trials allow us to recommend the use of the drug in the treatment of Ferrovir cytomegalovirus infection, generalized herpes infection, Genital herpes, HPV infection, when combined forms of HIV with hepatitis C, CMV and HSV.
According to clinical studies proven effective in combination, and in monotherapy HSV infection after a single intraperitoneal injection daily for 10 days. При лечении папилломавирусной инфекции – по 5 ml 1 time / day / m intervals 72 no. При лечении цитомегаловирусной инфекции – по 5 ml 1-2 times / day for 10 days.
Currently, cases of drug overdose were reported Ferrovir.
The drug is moderately potentiates the effect of anticoagulants, hepatoprotectors. When used in combination therapy reduces the toxicity and adverse effects of the drugs at the same time (headache, nausea).
The drug is released under the prescription.
The drug should be stored in a dark place at a temperature of 4 ° to 20 ° C. Shelf life - 5 years.
The solution for injection should be used immediately after opening the bottle; Do not store opened vials.
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