Enoksolon

When ATH: R02AA20

Pharmacological action

Antivirals for external and local application. Anti-inflammatory, analgesic effect, improves tissue regeneration.

It has activity against DNA- and RNA viruses, different strains of Herpes simplex virus and Herpes zoster.

The virus-inactivating, outside the cell, blocks the implementation of active viral particles through the cell membrane into the cell, It impairs the ability of viruses to the synthesis of new structural components; kinase inhibits virus and R (at concentrations, non-toxic to normal functioning cells), inhibits phosphorylation of cellular and virus-encoded proteins in infected cells.

Virus Strains, resistant to acyclovir and dioksiuridinu, may be sensitive to the drug.

Pharmacokinetics

The bioavailability of virus-infected cells to high. It accumulates in the lesions. Системная абсорбция – медленная.

Testimony

Viral infection of genitals, caused by Herpes simplex (acute primary, relapsing course); viral infection of the skin and mucous membranes in the mouth, nose and other regions of the body; a viral infection of the skin, caused by Herpes zoster.

Contraindications

Hypersensitivity.

Dosage regimen

Outwardly, spray is sprayed to the skin surface for a few seconds, from a distance 4-5 cm, 6 once a day for 5 days.

The cream is applied with a thin layer without rubbing 3-5 once a day for 3 days.

When persistent disease course, viral infection, вызываемой Herpes zoster – терапию проводят до полного исчезновения симптомов заболевания.

For the prevention of viral infections, передаваемых половым путем – применяют перед половым сношением.

Side effect

Allergic reactions.

Cautions

When a viral infection of the skin, caused by Herpes zoster, external treatment combined with oral administration of specific antiviral drugs.

During the full course of treatment decreases the frequency of relapses.

Aerosol has a neutral pH and does not irritate the skin and mucous membranes.

Drug Interactions

In an application with acyclovir, dioksiuridinom, интерфероном – потенцирование противовирусного действия.