Barbed Эleuterokokk – Eleutherococcus senticosus
Shrub 3-4 m, families aralievыh (Araliaceae). Distributed in the Primorye Territory and forests in the southern part of Sakhalin Island. For medical purposes, harvest the roots of plants.
Chemical composition Siberian ginseng
In the roots of Siberian ginseng contains glucose, sugar, starch, polisaxaridы, wax, resin, pectin, coumarin derivatives, and fatty oils, minerals, and eleuterozidy A, B, C, D, IS.
The pharmacological properties of Siberian ginseng
The extract of the roots of Eleutherococcus has low toxicity: LD50 rats by intraperitoneal injection is 14,5 g / kg. With long-term administration of the drug Eleutherococcus laboratory animals their relative harmlessness. Teratogenic not found. With prolonged use of Eleutherococcus extract experiment negative side effects were observed.
Siberian Ginseng Extract intravenous administration is a short-term drop in blood pressure, occurs immediately after administration. There is a certain dependence of the antihypertensive dose response study drug. The duration of the reaction to the introduction of the drug in blood pressure of 1-2 minutes.
Siberian Ginseng extract improves blood flow to the brain in laboratory animals, and anesthesia or extirpation of the cerebral cortex reduces the sensitivity of intracranial vessels and blood vessels of the retina to the action of Eleutherococcus. Its effect on the blood vessels of the brain and the eye fundus is carried out mainly through the sympathetic innervation. Under the influence of Eleutherococcus extract increased the diameter of the vessels and the exchange surface of the capillary bed of the heart. Preparations Eleutherococcus have gonadotrophic action in the event, if sex hormones occur active biosynthetic processes. At other times they are inactive.
In experimental studies, Siberian Ginseng extract found, that it has a pronounced stimulating and toning properties. Improving muscle performance under the influence of drugs Eleutherococcus is due lower costs of carbohydrate energy sources and earlier mobilization of lipids, coupled with phosphorylation and better preservation of the balance of muscle ATP, has a positive impact on the state of carbohydrate- phosphorus metabolism in brain tissue.
The study of the impact of drugs on the central nervous system of Eleutherococcus in the experiment revealed, that a single dose or long-term use of Siberian Ginseng extract increases the excitability of the cerebral cortex without any appreciable weakening of internal inhibition.
Besides, Siberian Ginseng extract has an activating effect on the electrical activity of the brain, reduces the degree of inhibitory action of chloral hydrate, barbital sodium and chlorpromazine on the activity of nerve elements of the brain. However, the drug has no significant effect on the functional state of the spinal cord intact animals.
In the study of the protective effect of drugs found Eleutherococcus, they increase the survival rate, lifespan of experimental animals, improve the biochemical parameters in traumatic brain injury in animals, with increased heat stability limit and other harmful effects of experimental. Influence of Eleutherococcus on the course of infection finally found.
The most extensively studied effect of anti-drug Eleutherococcus. Established, that the drugs reduce the duration of this plant is the hypnotic effect of sodium barbital, khloralgidrata. thiopental, ether, hexenal. Marked toxic effect of the extract of Eleutherococcus for acute and chronic poisoning with ethanol. On the background of Siberian Ginseng extract attenuated some of the effects of epinephrine, aminazina, sodium salicylate, reduced toxicity of the indole, alloksana, hydrochloride salt trihloretilamina, 6-merkaptopurina, tsnklofosfamyda, tiofosfamida, sarkolizina, With rubomycin.
The use of Siberian Ginseng in Medicine
The high therapeutic efficacy when taking Siberian Ginseng extract for 3-4 weeks has been established in patients with various forms of neurosis: treatment resulted in positive changes vagosympathetic relationship in most cases disappeared phenomenon vegetative dystonia.
Siberian Ginseng extract improves mental capacity of man, reduces fatigue during exercise, increases visual acuity and improves hearing in the studied. In appointing extract Eleutherococcus improves the general condition of patients, decreases cholesterol and lipoproteins in blood serum in atherosclerosis, mainly affecting the aorta and coronary vessels. Restorative effect Eleutherococcus creates a favorable background for the treatment of patients with various diseases of the cardiovascular system, including rheumatic heart disease.
The positive effect of the extract of Eleutherococcus noted in the use of his patients before surgery, wherein postoperative have flowed more smoothly.
Formulations, Dosing and Administration.
Siberian Ginseng Extract Liquid (Fluid extract Eleutherococci). Alcohol (on 40 % alcohol) extract (1:1) from rhizomes with roots Siberian ginseng appoint 2 ml for half an hour before a meal.
Available in jars. Store in a cool,, Protected from light.
