Efferalgan rectal suppositories for children: instructions for using the medicine, structure, Contraindications
Active material: paracetamol
When ATH: N02BE01
CCF: Analgesic-antipyretic
ICD-10 codes (testimony): J06.9, J10, K08.8, M79.1, M79.2, R50, R51, R52.0, R52.2
When CSF: 03.02.01.01
Manufacturer: BRISTOL-MYERS SQUIBB (France)
Efferalgan rectal suppositories for children: dosage form, composition and packaging
◊ Rectal Suppositories for children, smooth, glossy, white.
| 1 supp. | |
| paracetamol | 80 mg |
Excipients: semisynthetic glycerides (to the mass of the suppository 1 g).
5 PC. – packings Valium planimetric (2) – cardboard boxes.
◊ Rectal Suppositories for children, smooth, glossy, white.
| 1 supp. | |
| paracetamol | 150 mg |
Excipients: semisynthetic glycerides (to the mass of the suppository 1 g).
5 PC. – packings Valium planimetric (2) – cardboard boxes.
◊ Rectal Suppositories for children, smooth, glossy, white.
| 1 supp. | |
| paracetamol | 300 mg |
Excipients: semisynthetic glycerides (to the mass of the suppository 1.3 g).
5 PC. – packings Valium planimetric (2) – cardboard boxes.
Efferalgan rectal suppositories for children: pharmachologic effect
Analgesic-antipyretic. It has analgesic and antipyretic effect. Inhibits COX-1 and COX-2 mainly in the central nervous system, acting on pain centers and thermoregulation. It has a mild anti-inflammatory effect.
Efferalgan rectal suppositories for children: pharmacokinetics
Data on the pharmacokinetics Efferalgan in the form of rectal suppositories are not provided.
Efferalgan rectal suppositories for children: testimony
To children aged 3 months before 10 years:
- ARD, flu, childhood infections, post-vaccination reactions, other infectious and inflammatory diseases and conditions, accompanied by fever;
- Moderately or weakly expressed pain syndrome, incl. headache, toothache, muscle aches, neuralgia, pain in trauma and burns.
Efferalgan rectal suppositories for children: dosing regimen
The drug is used rectally. Freeing suppository from the pack, enter into the anus of the child (preferably after cleansing enema or spontaneous bowel movements).
The average single dose Efferalgan depends on the weight of the child and makes 10-15 mg / kg 3-4 times / day. The maximum daily dose – 60 mg / kg.
Children aged 5 years before 10 years (weighing from 20 to 30 kg) administered by 1 suppozytoryyu rectal (300 mg) 3-4 times / day at intervals 4-6 no. Do not apply more 4 suppositories per day.
Children aged 6 months before 3 years (weighing from 10 to 14 kg) administered by 1 suppozytoryyu rectal (150 mg) 3-4 times / day at intervals 4-6 no. Do not apply more 4 suppositories per day.
Children aged 3 to 5 months (weighing from 6 to 8 kg) administered by 1 suppozytoryyu rectal (80 mg) 3-4 times / day at intervals 4-6 no. Do not apply more 4 suppositories per day.
The duration of treatment is 3 of the day when used as antipyretic and to 5 days – as analgesic.
Efferalgan rectal suppositories for children: side effects
Allergic reactions: rarely – skin rash, itch, hives, angioedema.
From the digestive system: rarely – nausea, vomiting; With prolonged use at high doses may hepatotoxic effects, irritation of the mucous membrane of the rectum, tenesmus.
From the hematopoietic system: rarely – anemia, thrombocytopenia, leukopenia.
Other: With prolonged use at high doses may nephrotoxicity.
The drug was well tolerated at recommended doses.
With the development of adverse reactions is necessary to stop using the product and consult a doctor.
Efferalgan rectal suppositories for children: Contraindications
- Severe liver;
- Severe renal dysfunction;
- Blood disorders;
- Deficiency of glucose-6-fosfatdegidrogenazы;
- Recent inflammation or bleeding in the rectum;
- Children up to age 3 months (rectal suppository, containing 80 mg paracetamol);
- Children up to age 6 months (rectal suppository, containing 150 mg paracetamol);
- Children up to age 5 years (rectal suppository, containing 300 mg paracetamol);
- Hypersensitivity to paracetamol.
FROM caution use in patients with hepatic dysfunction or renal mild to moderate, when Gilbert's syndrome. Do not use in patients with diarrhea in the child.
Efferalgan rectal suppositories for children: Special instructions
Do not use in patients with diarrhea in the child.
In applying the drug more 7 days necessary to monitor patterns of peripheral blood and functional state of the liver.
Paracetamol distorts the results of laboratory studies of glucose and uric acid in the blood plasma.
Efferalgan rectal suppositories for children: overdose
Symptoms: nausea, vomiting, stomachache, Sweating, pale skin. Through 1-2 day show signs of liver damage. In severe cases develop liver failure, gepatonekroz, encephalopathy and coma.
Treatment: cancel product, patients need to consult a doctor.
Efferalgan rectal suppositories for children: drug interaction
In an application with barbiturates Efferalgan, anticonvulsants, rifampicin significantly increases the risk of hepatotoxicity.
In an application with chloramphenicol (chloramphenicol) the toxicity of the latter increases.
Paracetamol increases effects of indirect anticoagulants.
Before carrying out tests for uric acid and blood glucose should inform your doctor about the use of Efferalgan.
Efferalgan rectal suppositories for children: terms of dispensing from pharmacies
The drug is resolved to application as an agent Valium holidays.
Efferalgan rectal suppositories for children: terms and conditions of storage
The drug should be stored out of reach of children at or above 30 ° C. Shelf life – 3 year.
