Duovit
Active material: Combined multivitamin preparation
When ATH: A11AA04
CCF: Polyvitamins
ICD-10 codes (testimony): E50-E64, O99.2, Z73.0, Z73.3
When CSF: 17.03.04
Manufacturer: KRKA d.d. (Slovenia)
PHARMACEUTICAL FORM, COMPOSITION AND PACKAGING
Drop two species (40 PC. packaged):
| Red dragee (20 PC. v up.). | 1 drop |
| retinol palmitate (wreathed. A) | 2.94 mg |
| a-Tocopherol (wreathed. IS) | 10 mg |
| Kolekaltsiferol (wreathed. D3) | 200 g |
| vitamin C (wreathed. FROM) | 60 mg |
| tiamina mononitrat (wreathed. B1) | 1 mg |
| Riboflavin (wreathed. B2) | 1.2 mg |
| calcium pantothenate (wreathed. B5) | 5 mg |
| pyridoxine hydrochloride (wreathed. B6) | 2 mg |
| folic acid (wreathed. Bfrom) | 400 g |
| cyanocobalamin* (wreathed. B12) | 3 g |
| nicotinamide (wreathed. PP) | 13 mg |
* – цianokoʙalamin 0.1% in mannitol (3 mg)
Excipients: lactose monohydrate, orange oil 05073, polysorbate 80, glycerol, castor oil refined, sorbitol, Dextrose liquid, antifoam agent 1510, magnesium stearate, Opuluks dye AS-F-2833G (dye Ponceau 4r Puntsov (E124), colorant sunset yellow (E110)), wax emulsion, sucrose.
| Drage is blue (20 PC. v up.). | 1 drop |
| calcium hydrogen phosphate dihydrate | 64.5 mg, |
| which corresponds to the content of calcium (Ca2+) | 15 mg |
| which corresponds to the phosphorus content (P5+) | 12 mg |
| Magnesium lactate | 200 mg, |
| which corresponds to the content of magnesium (Mg2+) | 20 mg |
| iron fumarate | 30.3 mg, |
| which corresponds to the content of iron (Fe2+) | 10 mg |
| copper sulfate pentagidrate | 4 mg, |
| which corresponds to the content of copper (With2+) | 1 mg |
| zinc sulfate heptagidrate | 13.3 mg, |
| which corresponds to the content of zinc (Zn2+) | 3 mg |
| Manganese sulfate monohydrate | 3.1 mg, |
| which corresponds to the content of manganese (Mn2+) | 1 mg |
| sodium molybd digidrate | 220 g, |
| which corresponds to the content of molybdenum (Mo6+) | 100 g |
Excipients: lactose monohydrate, orange oil 05073, polysorbate 80, glycerol, castor oil refined, sorbitol, Dextrose liquid, antifoam agent 1510, magnesium stearate, Liquid paraffin, povidone, DDIGO CARAMINA AS-20912 Blue (E132), wax emulsion, sucrose.
10 PC.(5 PC. red dragees and 5 PC. Drage is blue) – blisters (4) – packs cardboard.
Pharmacological action
Combined polyvitamin preparation with micro- and macro elements, Contains the complex 11 vitamins and 8 minerals, It is an important factor of the metabolic processes.
One red and one blue dragee contain vitamins and minerals in quantities, satisfying the daily needs of the body. For better absorption of the vitamin-mineral complex and maintaining the activity of the main components, Vitamins and minerals are divided in dragees of different colors. Vitamins are found in red dragees, minerals – in blue drage.
Retinol (Vitamin A) involved in the synthesis of various substances (proteins, lipids, mukopolisaxaridov) and ensure the normal function of the skin, mucosas, as well as the organ of sight.
Kolekaltsiferol (vitamin D3) It plays an important role in maintaining the balance of calcium and phosphorus in the body. With its lack in bone calcium content decreases (osteoporosis).
Thiamin (vitamin B1) It normalizes the activity of the heart and promotes normal functioning of the nervous system.
Riboflavin (vitamin B2) promotes tissue regeneration, incl. skin cells.
Pyridoxine (vitamin B6) It helps to maintain the structure and function of bones, teeth, right; It affects erythropoiesis, It promotes normal functioning of the nervous system.
Цianokoʙalamin (vitamin B12) involved in erythropoiesis, It promotes normal functioning of the nervous system.
B vitamins are involved in the formation of different enzymes, that control different types of metabolism.
Folic acid (vitamin Bfrom) It stimulates erythropoiesis.
Tocopherol (Vitamin E) It is a natural antioxidant. Prevents increased blood coagulation and favorably affects peripheral blood circulation. Involved in the synthesis of proteins and hemoglobin, during cell growth, skeletal muscle function, Heart and Vascular, gonads.
Vitamin C (vitamin C) It participates in the oxidation of a number of biologically active substances, regulation of metabolism in the connective tissue, carbohydrate metabolism, blood clotting and tissue regeneration, It stimulates the production of steroid hormones, normalizes capillary permeability. Increases the body's resistance to infections, reduces the inflammatory response.
Calcium is involved in bone formation, blood clotting, transmission of nerve impulses, Reduction of skeletal and smooth muscle, normal operation of the heart. Promotes iron absorption.
Magnesium is involved in the formation of bone and muscle tissue, takes part in protein synthesis.
Iron is part of hemoglobin molecule, participates in the transfer of oxygen in the body and prevents the development of anemia.
Phosphorus is involved in the formation of bones and teeth, as well as in the processes of energy exchange.
Manganese promotes bone mineralization.
Copper is necessary for normal function of red blood cells and iron metabolism.
Zinc is necessary for tissue regeneration, part of some hormones, including insulin.
Pharmacokinetics
Action the preparation of the duovit® It is a combination of its components, is a kinetic observation is not possible. All components can be traced using markers or research.
Testimony
As a preventive agent in conditions, accompanied by an increase in the need for vitamins and minerals:
- increased physical activity (incl. during active sports);
- Pregnancy;
- Lactation;
- With irregular, inferior nutrition or a monotonous diet.
Dosage regimen
The drug should be taken inside after eating in the morning. Drops proglatyvayut, with a little water.
Adults and children over 10 years appoint 2 Drage/day (1 red dragees and 1 Drage is blue).
The course of the drug – 20 days. The course can be repeated after the break (1-3 month.) or on the recommendation of a doctor.
Side effect
Allergic reactions, including hypersensitivity reactions with an asthmatic component.
Contraindications
- Hypersensitivity to the drug.
Pregnancy and lactation
During pregnancy and during lactation, the drug can be used as prescribed by a doctor.
Cautions
The possible coloring of urine in yellow is harmless and is due to the presence of riboflavin in the drug.
Patients with diabetes should be considered, what 1 Drage contains 800 MG sugar, And the daily dose of the drug contains 1.6 g sugar.
Drage red and blue contains 331 Lactose mg, 1083 Sucrose mg, 270 mg of glucose, 237 mg sorbitol, Therefore, the drug is not recommended for patients with congenital intolerance to glucose and fructose, with glucose/galactose malabsorption syndrome and sugarize deficiency/isomaltase.
Azo dyes E124 and E110 can cause hypersensitivity reactions with an asthmatic component.
Hypersensitivity reactions are also possible in patients with increased sensitivity to acetylsalicylic acid.
Red dragees contain polio (mannitol), which in large doses can cause diarrhea.
Do not exceed daily dose. In case of accidental administration of the drug in a high dose, the patient should immediately consult a doctor.
It is not recommended to take duovite® in conjunction with other drugs, containing vitamins and minerals.
Overdose
Cases of an overdose when taking the drug in the recommended doses was not noted.
With a significant excess of recommended doses, cases of hypervitaminosis A and D are possible. The drug contains glycerol, Therefore, with an overdose, headache and disorders from the gastrointestinal tract are possible (incl. diarrhea, vomiting).
Drug Interactions
The drug contains iron and calcium and therefore slows down the absorption of antibiotics from the group of tetracyclines in the intestines, as well as derivatives of fluoroquinolons.
Vitamin C increases the effects and side effects of sulfonamides (incl. appearance of crystals in the urine).
Antacids, aluminum-containing, magnesium, calcium, as well as cholestyramine reduce the absorption of iron. Therefore, if necessary, the simultaneous use of duovite® and antacid drugs must observe the interval between techniques at least 3 no.
With the simultaneous use of diuretics from the Tiazid group, the likelihood of hypercalcemia increases.
Conditions of supply of pharmacies
The drug is resolved to application as an agent Valium holidays.
Conditions and terms
The drug should be stored out of reach of children, protected from light, dry place at temperatures no higher than 25 ° C. Shelf life – 3 year.
